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Could your age change how a nerve test reads your nerves?

NCT ID NCT07725120

Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This study looks at whether a person's age influences the accuracy of a nerve test called the sural-to-radial amplitude ratio (SRAR) in telling apart two types of peripheral neuropathy: length-dependent and non-length-dependent. Researchers will review medical records from about 180 adults with sensory polyneuropathy who had nerve tests as part of routine care. The goal is to see if using age-specific cutoff points could help doctors make a more precise diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If age-adjusted thresholds improve accuracy, doctors may better diagnose the type of neuropathy without extra tests.
What could go wrong
This is a small, single-center retrospective study, so results may not apply broadly. The test itself is not a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 180 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with peripheral sensory polyneuropathies evaluated at the Peripheral Neuromuscular Rare Disease Reference Center of Nice University Hospital between January 2013 and July 2026. Patients will be classified into length-dependent or non-length-dependent phenotypes and stratified into predefined age groups for analysis.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Diagnosis of peripheral sensory polyneuropathy. * Classification as length-dependent (LDN) or non-length-dependent (NLDN) based on clinical and electrophysiological findings. * Available nerve conduction study including sural and radial sensory nerve amplitudes allowing calculation of the SRAR. * Evaluated at the Peripheral Neuromuscular Rare Disease Reference Center, Nice University Hospital, between January 2013 and July 2026. Exclusion Criteria: * Missing or incomplete clinical or electrophysiological data preventing SRAR calculation. * Unclassifiable neuropathy phenotype. * Technical factors affecting the reliability of nerve conduction studies.

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Conditions

The condition(s) this trial relates to.

polyneuropathy sensory peripheral neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diagnostic techniques Electromyography Polyneuropathies

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU de Nice

    Nice, Alpes Maritimes, 06000, France

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