New hope for leprosy patients: experimental drug targets painful skin flares

NCT ID NCT07172659

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests an experimental drug called dovramilast for people with moderate to severe leprosy type 2 reaction, a painful skin condition. About 45 adults will receive either 100 mg or 150 mg of dovramilast or standard treatments for 12 weeks. The goal is to see if the new drug can reduce skin lesions and improve fever safely.

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Contacts and locations

Locations

  • Centre de Dépistage de Traitement de la Lèpre et de l'Ulcère de Burulli

    Abomey-Calavi, Benin

  • Chr de Divo

    Divo, Côte d’Ivoire

  • Harborview Medical Center, University of Washington

    Seattle, Washington, 98104, United States

  • Philippine General Hospital, University of the Philippines, Manila

    Manila, Philippines

  • Universitas Gadjah Mada

    Yogyakarta, Indonesia

  • University of Southern California

    Los Angeles, California, 90007, United States

Conditions

Explore the condition pages connected to this study.