Burkholderia infectious disease

This study tests a combination of two antibiotics, aztreonam and avibactam, in newborns and infants up to 9 months old who have serious infections caused by gram-negative bacteria. The trial has two parts: one to see how a single dose moves through the body, and another to test m…

This study tests whether adding a second antibiotic (fosfomycin) to the standard antibiotic (ceftazidime) helps people with severe gram-negative infections recover faster. About 100 hospitalized adults will be randomly assigned to get either the combo or the standard drug plus a …

This study aims to understand how the environment, the bacteria that cause melioidosis, and the human body interact to cause disease. Researchers will follow about 1,000 infected patients and 1,000 healthy matched controls in Thailand, Laos, and Cambodia for one year. They will a…

This study observes 600 patients in Korea who receive Zavicefta for complicated abdominal or urinary tract infections or hospital-acquired pneumonia. Researchers track side effects and how well the drug works. It is required by Korean regulators to ensure the drug's safety after …

This study will test 10,000 people in Cambodia for 57 different infectious diseases, including dengue, flu, and malaria. Researchers want to understand how these diseases spread and who is at risk. The goal is to give local health authorities the information they need to create b…