Scientists hunt for genetic clues to severe infections in kids

NCT ID NCT07111793

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand why some children develop severe bacterial infections that require intensive care. Researchers will analyze blood samples and medical histories from 1,401 children who were hospitalized for such infections between 2015 and 2018 in France. By comparing their genetic and immune profiles to healthy controls, the team hopes to identify inherited factors that increase risk. The study does not test any new treatment but focuses on gathering knowledge.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors identify children at higher risk for severe bacterial infections and guide personalized prevention or treatment strategies.

What could go wrong

This is an observational study, not a treatment trial. It may not find clear genetic links, and results may take years to translate into practical medical advice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • CHU de Brest

    NOT_YET_RECRUITING

    Brest, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Saint-Étienne

    NOT_YET_RECRUITING

    Saint-Etienne, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospices Civils de Lyon

    NOT_YET_RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Armand Trousseau

    NOT_YET_RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Necker enfants malades

    NOT_YET_RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nantes University Hospital

    RECRUITING

    Nantes, Loire Atlantique, 44093, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••