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Scientists hunt for genetic clues to severe infections in kids

NCT ID NCT07111793

Recruiting now Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand why some children develop severe bacterial infections that require intensive care. Researchers will analyze blood samples and medical histories from 1,401 children who were hospitalized for such infections between 2015 and 2018 in France. By comparing their genetic and immune profiles to healthy controls, the team hopes to identify inherited factors that increase risk. The study does not test any new treatment but focuses on gathering knowledge.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify children at higher risk for severe bacterial infections and guide personalized prevention or treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear genetic links, and results may take years to translate into practical medical advice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE BACTERIAL INFECTIONS

Contacts and locations

Locations

  • CHU de Brest

    NOT_YET_RECRUITING

    Brest, France

  • CHU de Saint-Étienne

    NOT_YET_RECRUITING

    Saint-Etienne, France

  • Hospices Civils de Lyon

    NOT_YET_RECRUITING

    Lyon, France

  • Hôpital Armand Trousseau

    NOT_YET_RECRUITING

    Paris, France

  • Hôpital Necker enfants malades

    NOT_YET_RECRUITING

    Paris, France

  • Nantes University Hospital

    RECRUITING

    Nantes, Loire Atlantique, 44093, France

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