New study aims to cut unnecessary antibiotics in ICU patients

NCT ID NCT07211620

Recruiting now Knowledge-focused Sponsor: Semmelweis University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using changes in procalcitonin levels over time (kinetics) is better than a single measurement for deciding when to start antibiotics in critically ill patients with suspected infection. About 250 adults in the ICU will be randomly assigned to one of two groups. The goal is to reduce unnecessary antibiotic use while ensuring patient safety.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease Infections infectious disease infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFECTION SEPSIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Saint Margaret's Hospital
NOT_YET_RECRUITING

Budapest, 1032, Hungary

Contact Phone: •••-•••-•••• Email: •••••@•••••
Semmelweis University, Department of Intensive Therapy
RECRUITING

Budapest, 1082, Hungary

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••