Semmelweis University

This study compares two ways to treat deep bone defects in the gums caused by gum disease. One method is a minor surgery (MIST) and the other is a deep cleaning (GBT), both combined with a substance made from the patient's own blood (platelet-rich fibrin) to help healing. About 3…

This study tests whether a custom 3D-printed implant can safely drain jaw cysts, avoiding more invasive surgery. Twenty patients with odontogenic cysts near important jaw structures will receive the implant after a small surgical opening. The implant stays in place with tiny scre…

This study tests a synthetic bone graft material (biphasic calcium sulfate) used during sinus lift surgery to rebuild bone in the upper jaw. The goal is to see if it safely creates enough bone to place dental implants in people who lack sufficient bone due to sinus expansion. For…

This study compares two methods of rebuilding the jawbone for people who need dental implants but have lost bone after tooth loss. One method uses a piece of the patient's own bone, while the other uses donated, freeze-dried bone. The goal is to see if the donated bone works just…

This study aims to create a step-by-step guide for adapting a children's speech hearing test, called MATCH, into different languages. Researchers will test the adapted test on 120 children, including those with normal hearing and those with hearing loss, to make sure it works cor…

This study looks at giving hydrocortisone, a steroid, to newborns with brain injury from lack of oxygen who are being cooled and have low blood pressure. Researchers want to find the best dose for each baby by measuring steroid levels in the blood. The goal is to safely raise blo…

This study tests whether a virtual reality (VR) simulation of an MRI scan can help children aged 4-18 stay calm enough to complete the real scan without anesthesia. About 288 children will be randomly assigned to VR preparation, a booklet, or usual care. The main goal is to see i…

This study tests whether online or group physiotherapy can be as effective as individual in-person sessions for treating jaw muscle pain (TMD). About 90 adults with jaw muscle pain will be randomly assigned to one of three treatment formats. The goal is to find more accessible wa…

This study follows 100 people newly diagnosed with esophageal cancer in Hungary. Researchers will track heart function, nutrition, physical ability, and mental health before and after surgery. The goal is to find which factors are linked to better survival and quality of life, so…

This study tests whether using changes in procalcitonin levels over time (kinetics) is better than a single measurement for deciding when to start antibiotics in critically ill patients with suspected infection. About 250 adults in the ICU will be randomly assigned to one of two …

Researchers at Semmelweis University are studying 600 children aged 1.5 to 6 years in Hungary to see how common autistic traits and feeding difficulties are, and whether they are linked. The study includes children with and without autism. The goal is to gather information, not t…