Semmelweis University

This study compares two methods of rebuilding the jawbone for people who need dental implants but have lost too much bone. One method uses a piece of the patient's own bone, and the other uses donated (allograft) bone. The goal is to see which works better, causes fewer complicat…

This study tests a new bone graft material called biphasic calcium sulfate for sinus lift surgery. The surgery adds bone to the upper jaw so dental implants can be placed. Forty adults who need implants but lack enough bone will receive the graft and be followed for 3 to 6 months…

This study compares two ways to treat deep gum bone defects: a minor surgery (MIST) or a deep cleaning method (GBT), both combined with a natural healing aid called platelet-rich fibrin (PRF). About 36 adults with a single deep defect will be randomly assigned to one treatment. T…

This study looks at how to best give hydrocortisone to newborns with low blood pressure who are being cooled for brain injury caused by lack of oxygen at birth. About 50 full-term babies will receive the drug while doctors monitor their blood pressure and drug levels. The goal is…

This study tests whether custom-made implants can help treat odontogenic cysts (fluid-filled sacs in the jaw) by decompressing them. About 20 patients with cysts near important jaw structures will receive the implant, which is anchored with small screws. The goal is to see if the…

This study aims to create a step-by-step guide for translating and adapting a children's speech hearing test (called MATCH) into other languages. Researchers will test the adapted version in 120 children, both with normal hearing and with hearing loss, to ensure it works correctl…

This study tests whether a virtual reality simulation that mimics an MRI scan can help children aged 4-18 stay calm enough to complete the real scan without anesthesia. About 288 children will either use the VR prep, read a booklet, or receive usual care before their MRI. The mai…

This study tests whether online or group physiotherapy can be as effective as individual sessions for treating jaw muscle pain (temporomandibular disorders). About 90 adults with jaw muscle pain will be randomly assigned to one of three treatment formats. The goal is to see if mo…

This study aims to find out how common autistic traits and feeding problems are among young children in Hungary. Researchers will observe 600 children aged 1.5 to 6 years, including those with autism, those showing signs, and typically developing kids. The goal is to better under…

This study follows 100 people in Hungary newly diagnosed with esophageal or stomach-junction cancer. Researchers will use non-invasive tests, blood biomarkers, and questionnaires to track changes in heart function, nutrition, physical ability, and mental health before and after s…

This study tests whether looking at how a blood marker (procalcitonin) changes over time is better than a single measurement for deciding when to start antibiotics in critically ill patients. About 250 adults in the ICU with a suspected infection will be randomly assigned to one …