Semmelweis University
Clinical trials sponsored by Semmelweis University, explained in plain language.
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Digital device shrinks jaw cysts before surgery
Disease control CompletedThis study tested a new way to treat odontogenic cysts (fluid-filled sacs in the jawbone) using a custom-made, 3D-printed device. The device was placed right after a small opening was made in the cyst, allowing it to slowly shrink over time before being surgically removed. Fiftee…
Phase: NA • Sponsor: Semmelweis University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Blood clot gel vs tooth protein: which fixes gum bones better?
Disease control CompletedThis study tested two treatments for deep gum bone defects caused by periodontitis: platelet-rich fibrin (PRF), made from the patient's own blood, and enamel matrix derivative (EMD), a protein gel. Twenty-six patients received one of the treatments after surgery, and their gum he…
Phase: PHASE4 • Sponsor: Semmelweis University • Aim: Disease control
Last updated Jun 26, 2026 19:19 UTC
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New surgical trick may save your gums while straightening teeth
Prevention CompletedThis study tested a procedure called Periodontally Accelerated Osteogenic Orthodontics (PAOO) in 20 adults getting braces. The goal was to see if it could prevent bone loss and gum recession on the front of the lower teeth. The procedure combines a small cut in the gum with a bon…
Phase: NA • Sponsor: Semmelweis University • Aim: Prevention
Last updated Jun 27, 2026 12:25 UTC
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New study shows simple exercises can prevent shoulder injuries in young handball stars
Prevention CompletedThis study tested two shoulder injury prevention programs in 137 teenage handball players (ages 13-19) from a Hungarian academy. Over 18 weeks, players did exercises from either a Swedish or Norwegian program. The study measured shoulder function, control, and injury rates. Both …
Phase: NA • Sponsor: Semmelweis University • Aim: Prevention
Last updated Jun 27, 2026 08:08 UTC
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Talking it out: group therapy may ease eczema symptoms
Symptom relief CompletedThis pilot study tested whether adding group psychotherapy to standard care can help adults with moderate-to-severe atopic dermatitis (eczema). Thirty-two participants were assigned to either standard care alone, standard care plus stress management and resilience training, or st…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Talking teens out of pain: can motivation and Self-Management help?
Symptom relief CompletedThis study tested whether a short motivational interview combined with self-management techniques could help Hungarian teens aged 12-18 who have had chronic pain for at least 3 months. The program included a 30-minute in-person session plus two follow-up phone calls. Researchers …
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Brain zaps show promise for tough schizophrenia symptoms
Symptom relief CompletedThis study tested a type of brain stimulation called theta-burst TMS to see if it can safely improve negative symptoms (like lack of motivation) and thinking problems in people with schizophrenia. 76 adults with stable schizophrenia took part in a double-blind trial where some re…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New Step-by-Step training helps seniors get up safely after a fall
Symptom relief CompletedThis study tested a training method called backward chaining to teach elderly nursing home residents how to get up from the floor. Twenty-six participants were randomly assigned to either the training group or a control group. The training involved 20 sessions led by a physiother…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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VR goggles could replace pills for teen surgery anxiety
Symptom relief CompletedThis study tested whether using a virtual reality headset during and after chest surgery could help teenagers feel less anxious and need fewer painkillers. Fifty teens aged 13-18 having a specific chest surgery (MIRPE) were randomly assigned to use VR or not. Researchers measured…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated Jun 26, 2026 14:40 UTC
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Mouth ridge ID tested after dental expansion
Knowledge-focused CompletedThis study looked at whether the unique ridges on the roof of the mouth (palatal rugae) can still be used to identify a person after they have had dental expansion treatment. Researchers used 3D scans from 45 people before and after treatment to see if the ridges remained distinc…
Phase: NA • Sponsor: Semmelweis University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Does breast cancer drug trastuzumab cause dry eye?
Knowledge-focused CompletedThis completed study from Semmelweis University looked at whether the breast cancer drug trastuzumab (Herceptin) causes dry eye or other eye surface problems. 35 adults with HER2-positive breast cancer took the drug as prescribed and visited the clinic every 3 months for eye exam…
Sponsor: Semmelweis University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Jaw study aims to find best expansion method for adults
Knowledge-focused CompletedThis study looked at two different methods to widen the upper jaw in adults: one with surgery and one without. About 50 adults took part and were followed for 12 months. Researchers used 3D scans to measure how well each method worked and how stable the results were. The findings…
Phase: NA • Sponsor: Semmelweis University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New lung nodule marking method could replace CT-Guided technique
Knowledge-focused CompletedThis completed trial with 66 participants compared two methods for marking small lung nodules before minimally invasive surgery: navigational bronchoscopy using a green dye (ICG) and CT-guided radioisotope injection. The goal was to see which method helps surgeons find and remove…
Phase: NA • Sponsor: Semmelweis University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:12 UTC