New lung nodule marking method could replace CT-Guided technique

NCT ID NCT06957600

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This completed trial with 66 participants compared two methods for marking small lung nodules before minimally invasive surgery: navigational bronchoscopy using a green dye (ICG) and CT-guided radioisotope injection. The goal was to see which method helps surgeons find and remove nodules faster and more completely. Researchers also checked for complications and surgeon satisfaction. Results could guide which technique is safer and more effective.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Preoperative marking (navigational bronchoscopy with ICG dye or CT-guided radioisotope)
What this could lead to
If successful, this could show that navigational bronchoscopy is a safer, radiation-free alternative for marking lung nodules before surgery, potentially improving surgical outcomes.
What could go wrong
This is a small, completed trial with only 66 participants, so results may not apply to all patients. Both methods are already in use, so no major breakthrough is expected.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Semmelweis University- National Institute of Oncology Department of Thoracic Surgery

    Budapest, Budapest, 1122, Hungary

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Other studies related to the condition(s) this trial covers.