Antibiotic shot under skin could replace IV drip for serious infections
NCT ID NCT07481539
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a powerful antibiotic called piperacillin/tazobactam can be given as a continuous shot under the skin instead of through an IV line. About 240 adults with serious bacterial infections will be randomly assigned to receive the drug either subcutaneously or intravenously. The main goal is to see if the subcutaneous method provides similar drug levels in the blood and is safe. If it works, this could make treatment more convenient and less invasive.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Piperacillin/tazobactam (antibiotic combination)
What this could lead to
If successful, this could offer a simpler, less invasive way to deliver a powerful antibiotic, potentially reducing hospital stays and discomfort for patients.
What could go wrong
This is a Phase 2 trial with only 240 participants, so results are preliminary. The subcutaneous route may not achieve the same drug levels as IV, and there could be injection-site reactions or other safety issues.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BACTERIA INFECTION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Azienda Sanitaria Universitaria Friuli Centrale
RECRUITINGUdine, Italia/UD, 33100, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••