Cat bite antibiotics: could less be more?

NCT ID NCT05846399

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 31 times

Summary

This study looks at whether taking antibiotics for just one day after a cat bite to the hand or forearm works as well as the usual five-day course, or even a placebo. About 72 adults who are bitten and seek care within 24 hours will be randomly assigned to one of three groups. The goal is to see if shorter treatment can prevent infections without increasing harm.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Missouri

    RECRUITING

    Columbia, Missouri, 65212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Amoxicillin/clavulanate (or alternatives ciprofloxacin and clindamycin)

What this could lead to

If successful, this could show that a shorter course of antibiotics or even no antibiotics is safe after a cat bite, reducing unnecessary medication and side effects.

What could go wrong

This is a small, early-phase trial with only 72 participants, so results may not apply to everyone. There is a risk that shorter treatment or placebo leads to more infections.

Conditions

The condition(s) this trial relates to.

Arm Injuries bacterial infectious disease Hand Injuries injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.