Yale University

This study tests a community program to improve asthma care for 50 children in New Haven. It combines online tools for doctors with home visits from health workers (Promotoras) who provide culturally sensitive support and connect families to legal and medical services. The goal i…

This study looks at whether surgically removing the prostate, along with hormone therapy and possibly chemotherapy, can help men with prostate cancer that has spread to other parts of the body. About 190 men will be randomly assigned to receive either standard therapy alone or st…

This study tests whether a low-caffeine green tea extract (EGCG) can shrink uterine fibroids and improve pregnancy and live birth rates in women aged 18-40 with infertility. About 50 women will take the extract and be monitored for conception, miscarriage, and fibroid changes. Th…

This study looks at whether a community health worker can help people with type 2 diabetes and low income use a program that gives them free fruits and vegetables. About 116 Hispanic adults in Connecticut will take part. The goal is to see if having a health coach helps them eat …

This study tests a two-step treatment for people with pancreatic cancer that is too advanced for surgery but hasn't spread to other organs. First, patients receive a stronger chemotherapy regimen called modified FOLFIRINOX, followed by precise, high-dose radiation (SBRT). The goa…

This study tests whether a weekly injection of semaglutide can help preserve the body's ability to produce insulin and reduce fat buildup in the liver. It involves 60 obese teenagers with prediabetes or early type 2 diabetes who also have fatty liver disease. The goal is to see i…

This study looks at whether the Bright Bodies program can help children ages 7 to 13 with obesity lower their body mass index (BMI). About 182 children and their parents will take part in the program at three different health centers. The program focuses on healthy eating, physic…

This study is testing a digital program called LDART to see if it helps adults who use stimulants like cocaine or methamphetamine. Researchers want to know if people find it easy to use and if it helps them use less. About 80 people from Connecticut will try the program for 28 da…

This study aimed to see if Botulinum Toxin-A (Botox) could help people with hidradenitis suppurativa, a painful skin condition that causes boils and abscesses. Researchers planned to inject Botox into the armpits of adults with active disease and track changes in lesion count and…

This early-phase study tests whether BHV-7000, a drug that activates potassium channels, can reduce abnormal electrical activity in the brains of people with focal epilepsy who have an implanted RNS device. Five participants will take the drug for 4 weeks, and their brain recordi…

This study tests a new behavior therapy designed to help teenagers with autism manage irritability and aggression. The therapy teaches emotion regulation and coping skills for the challenges of growing up. Researchers will measure changes in aggressive behavior and irritability i…

This study aimed to see if a guided reflective writing program could reduce burnout in physician assistant students at Yale. It was designed to compare students who took part in the program with those who did not. However, the study was withdrawn before enrolling any participants…

This study looks at whether a virtual music and mindfulness program can help People of African Descent (ages 18+) manage stress, anxiety, and depression during COVID-19. Participants will join drum circles and rate their feelings of connection and synchrony. The goal is to unders…

This study tests a tool called ED-TREAT that helps emergency room staff detect and treat agitation early. It includes 26 adults who are at risk of agitation but calm at arrival. The goal is to see if the tool is easy to use and works well in practice.

This research project follows 458 people with critical limb-threatening ischemia, a severe form of peripheral artery disease that can lead to amputation. The goal is to learn from patients' experiences and medical records to set new standards for diagnosis and care. No new treatm…