New hope for brain cancer? drug duo targets tough tumors
NCT ID NCT04656535
First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 32 times
Summary
This early-stage study tests two immunotherapy drugs (domvanalimab and zimberelimab) in people whose glioblastoma has come back after initial treatment. The goal is to check safety and see how the drugs affect the tumor and immune system. About 46 participants will receive the drugs before surgery or as a safety check.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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University of California San Francisco
San Francisco, California, 94143, United States
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Yale University
New Haven, Connecticut, 06519, United States
Conditions
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