Yale University
Clinical trials sponsored by Yale University, explained in plain language.
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Heart drug digoxin tested for Alcohol-Liver damage – early trial ends early
Disease control TerminatedThis small, early-phase trial tested whether the heart medication digoxin could reduce inflammation in people with severe alcohol-associated hepatitis. 23 participants were randomly assigned to receive either intravenous digoxin or no digoxin for up to 28 days. The study was term…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 22, 2026 11:55 UTC
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New combo tackles brain tumors in melanoma and kidney cancer patients
Disease control TerminatedThis study tested a combination of two drugs, pembrolizumab and lenvatinib, in 18 adults with melanoma or kidney cancer that had spread to the brain. Participants had already received anti-PD-1/PD-L1 therapy. The goal was to see if the drug combo could shrink or eliminate brain t…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 16, 2026 12:50 UTC
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New alarm aims to stop bedwetting: study tests effectiveness
Symptom relief TerminatedThis study tested a new bedwetting alarm called GoGoband against a standard alarm in children and young adults aged 6 to 21 with nighttime bedwetting. The goal was to see which alarm led to more dry nights. The study was stopped early and included only 16 participants, so results…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 18, 2026 11:48 UTC
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Face stretch study explores link between touch and speech
Knowledge-focused TerminatedThis study looked at whether repeatedly pairing facial skin stretches with speech sounds can change how people perceive speech. Researchers tested 160 right-handed adults with no known neurological issues. The study was terminated early, so results are limited.
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 23, 2026 15:16 UTC
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Brain zap study probes how we remember new speech moves
Knowledge-focused TerminatedThis study looked at whether brain areas that process touch and hearing help us remember how to adjust our speech after learning. Researchers used magnetic pulses to temporarily quiet those brain areas in healthy adults after they adapted their speech sounds. The trial was termin…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:55 UTC
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Hope or hype? tiny study on esketamine and pep talks ends early
Knowledge-focused TerminatedThis study aimed to see if giving extra encouragement and reassurance to people receiving esketamine for depression could improve their treatment outcomes. Researchers planned to compare a group that got a positive presentation before treatment and a follow-up session after, vers…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:57 UTC
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Simple Pre-Surgery test may spot hidden heart damage
Knowledge-focused TerminatedThis study tested whether a brief, low-intensity exercise test before noncardiac surgery could help doctors detect heart injury after surgery better than standard care. Ten adults aged 45 or older participated. Researchers measured heart injury using a blood test for up to three …
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:48 UTC
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Brain zapping study reveals Memory's role in speech learning
Knowledge-focused TerminatedThis study looked at how memory for speech sounds and movements helps people learn to speak. Researchers used a gentle magnetic pulse to temporarily quiet a part of the brain linked to memory, then tested how well healthy adults could adjust their speech. The goal was to understa…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:02 UTC