Yale University
Clinical trials sponsored by Yale University, explained in plain language.
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New device aims to ease stroke hand pain and improve movement
Symptom relief CompletedThis study tested a new device called Miraπ that physically moves a stroke patient's affected hand during mirror therapy. It compared this device to standard mirror therapy in 24 stroke patients with hand paralysis and pain. The goal was to see if the device could better improve …
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated May 01, 2026 18:26 UTC
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New app aims to help heavy drinkers quit or cut back
Symptom relief CompletedThis study tested whether a web-based social support program is practical and helpful for people who drink heavily and want to reduce their alcohol use. Thirty adults in Connecticut used the tool for 28 days. The goal was to see if people would use it and find it supportive, not …
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
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Brain app shows promise for easing depression in cancer and kidney patients
Symptom relief CompletedThis study tested a digital neurotherapy (a computer-based program) to see if it could help with depression, thinking skills, and quality of life in 36 people with serious illnesses—cancer survivors and patients with end-stage kidney disease on dialysis. Participants were randoml…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
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CBD shows promise for opioid addiction and pain relief in small study
Symptom relief CompletedThis early-stage study tested whether cannabidiol (CBD) could safely help people with both opioid addiction and chronic pain. Seven adults on methadone or buprenorphine received CBD or a placebo in a crossover design. Researchers measured sedation, cognitive function, side effect…
Phase: EARLY_PHASE1 • Sponsor: Yale University • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
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Teens try online program to curb binge eating
Symptom relief CompletedThis small pilot study tested an online guided self-help program for teens aged 12 to 17 who have binge eating episodes and a higher body weight. Over four months, participants completed weekly online sessions and were interviewed afterward. The goal was to see if the program was…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated May 01, 2026 15:57 UTC
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Computer prompts help doctors tackle childhood obesity
Knowledge-focused CompletedThis study looked at whether special computer reminders in electronic health records help doctors better follow guidelines for managing overweight and obesity in children. Over 58,000 children and their doctors took part across multiple primary care clinics. The goal was to see i…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 18:37 UTC
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Navigating blindness: new study tests simple solution for diabetic eye disease
Knowledge-focused CompletedThis study tested a program where a patient navigator helped 35 adults with diabetes who had not had an eye exam in the past year. The goal was to see if this support could help them get the eye exams needed to catch diabetic retinopathy early and prevent blindness. The study foc…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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New imaging technique could reveal how well PAD treatments work
Knowledge-focused CompletedThis study tested whether a special type of scan (SPECT/CT) can measure blood flow in leg muscles of people with peripheral artery disease (PAD) and diabetes. Researchers compared scans from healthy volunteers and patients before and after a procedure to open blocked leg arteries…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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New study aims to boost opioid treatment in ERs
Knowledge-focused CompletedThis study tested different methods to help emergency room doctors start medication (buprenorphine) for patients with opioid use disorder. Over 1,100 patients took part. Researchers compared tools like nurse prompts and patient resources to see which best increased treatment rate…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Lab test: does endotoxin fuel alcohol cravings?
Knowledge-focused CompletedThis study looked at whether a bacterial substance called endotoxin increases drinking in people with alcohol use disorder. 27 adults took part in a lab session where they could drink alcohol after receiving either endotoxin or a placebo. The goal was to see if endotoxin changes …
Phase: PHASE2 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Phone chatbots and mouth swabs could revolutionize TB tracking
Knowledge-focused CompletedThis study tested a new way to find people who may have been exposed to tuberculosis (TB) in Cali, Colombia. Researchers used a smartphone chatbot and an easy mouth-swab test that people could do at home. The goal was to see if this approach was practical and acceptable for track…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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New biopsy technique aims to decode prostate cancer cell by cell
Knowledge-focused CompletedThis study tested a new way to collect and analyze prostate cancer cells using MR-US image fusion targeted biopsy. Researchers grew cells from 600 men in the lab to study their unique protein and genetic profiles. The goal was to better predict how aggressive a person's prostate …
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Can earlier preschool boost Kids' brains and Moms' wallets? kenya study says maybe.
Knowledge-focused CompletedThis study looked at whether letting children in rural Kenya start preschool at age 3, instead of the usual age 4, helps them learn better and allows their mothers to work more. Over 2,000 children and their families took part. Researchers measured kids' thinking and language ski…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Brain scan study hopes to unlock memory treatments for schizophrenia
Knowledge-focused CompletedThis study looked at whether an experimental drug (CVL-562) can change brain activity related to working memory in people with early schizophrenia. About 112 participants completed memory tasks while having their brains scanned. The goal was to find brain markers that could help …
Phase: PHASE2 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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VR headset aims to recreate psychedelic experience without drugs
Knowledge-focused CompletedThis study tested a virtual reality program (DeepDream) to see if it could produce feelings similar to a psychedelic drug experience. Ten healthy volunteers tried the VR and reported their experiences using standard questionnaires. The goal was to explore whether VR could be a sa…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Brain scans reveal how stress changes learning
Knowledge-focused CompletedThis study looked at how short-term stress changes the way the brain learns and remembers. Researchers used brain scans (fMRI) to measure brain activity in 106 healthy adults while they performed learning tasks. The goal was to understand the brain mechanisms behind stress effect…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Can a simple test spot stoned drivers? new study investigates
Knowledge-focused CompletedThis study looked at how smoking cannabis affects thinking and driving skills in 41 adults aged 18-55 who are regular users. Participants completed thinking tasks and a driving simulator before and after using cannabis. The goal was to find reliable ways to measure marijuana impa…
Phase: PHASE1 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC