Portable MRI could bring brain scans to your local clinic
NCT ID NCT06533631
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a portable, low-field MRI machine to see if it can measure white matter hyperintensities (WMH) in the brain—a sign of small vessel disease. Researchers compared the portable MRI to the standard high-field 3T MRI in 100 adults with at least one vascular risk factor (like high blood pressure). The goal was to create a simple grading scale for WMH using the portable device, which could make brain health monitoring easier and more accessible.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Portable low-field MRI (pMRI) device
- What this could lead to
- If successful, this portable MRI could make brain health monitoring more accessible and affordable, especially in clinics or remote areas.
- What could go wrong
- This is a small, completed study focused on developing a new grading scale, not on treating disease. The portable MRI may not be as accurate as standard MRI for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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100 people
The number who actually took part.
- Started
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Feb 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants, age 50+, with risk factors for white matter hyperintensities, including hypertension, hyperlipidemia and diabetes. Patients may be identified through flyers distributed among outpatient clinics at Yale-New Haven Hospital for general neurology, internal medicine, and preventive cardiology.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * One vascular risk factor, from the following: 1. Hypertension (defined as taking an antihypertensive medication) 2. Hyperlipidemia (defined as taking a statin or PCSK9 inhibitor) 3. Diabetes (defined as taking a medication to prevent hyperglycemia) Exclusion Criteria: * 1\. History of stroke * History of dementia or other cognitive impairment * Pacemaker or other MRI contraindications according to the American College of Radiology guidelines
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Yale Magnetic Resonance Research Center (MRRC) at The Analyn Center (TAC)
New Haven, Connecticut, 06520, United States
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