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Brain zap may wake people during seizures when drugs fail

NCT ID NCT04897776

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 27 times

Summary

This study tested a new way to help people with temporal lobe epilepsy who still have seizures despite medications or other treatments. Instead of trying to stop the seizure, the approach uses mild electrical stimulation in the thalamus (a deep brain area) to help the person stay conscious during the seizure. Five adults took part, and the researchers measured awareness using a tablet-based test during seizures.

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Contacts and locations

Locations

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.