EPILEPSY, TEMPORAL LOBE

This study tests brain surgery for children and adults with epilepsy that medication cannot control. Participants will have surgery to remove or treat the part of the brain causing seizures. The goal is to stop or greatly reduce seizures, though some patients may still need ongoi…

This early-stage trial tests a single injection of special nerve cells (NRTX-1001) into both sides of the brain for people with severe epilepsy that doesn't respond to medication. The goal is to see if it's safe and can reduce seizure frequency. Ten adults aged 18-75 with confirm…

This study tests a device called NaviFUS™ that uses low-intensity focused ultrasound to calm overactive brain areas causing seizures. It is for adults with epilepsy that does not respond to medication. The goal is to see if this treatment can safely reduce seizure frequency. Sixt…

This study tests a new MRI technique using ferumoxytol to get clearer images of tiny blood vessels in the brain's memory center. It involves 50 adults with temporal lobe epilepsy and healthy volunteers. The goal is to find better ways to predict who will benefit most from epileps…

This study aims to understand how the brain recognizes and remembers places, which is often impaired in people with temporal lobe epilepsy. Researchers will use a virtual tour task and brain recordings (EEG, intracranial EEG) in 620 participants, including epilepsy surgery patien…

This study aims to better understand epilepsy and find new ways to help people whose seizures don't improve with medication. Researchers will screen up to 1,000 adults and children aged 8 and older using tests like brain scans and EEGs. The goal is to identify participants who ma…

This study aims to improve how doctors plan epilepsy surgery by using advanced MRI scans to map brain connections. Researchers will compare these scans with electrical recordings from inside the brain in 290 people with drug-resistant epilepsy. The goal is to develop noninvasive …