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Virtual tours may help spare memory in epilepsy surgery

NCT ID NCT07580183

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores how the brain recognizes and remembers places, using virtual tours and brain recordings in people with epilepsy. Researchers aim to map the brain regions critical for spatial memory, so surgeons can avoid them during epilepsy surgery. Over 600 participants, including epilepsy patients and healthy volunteers, will complete memory tasks while their brain activity is measured. The goal is to reduce memory loss after surgery by better understanding the brain's memory circuits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors predict and prevent memory problems after epilepsy surgery, leading to better cognitive outcomes for patients.
What could go wrong
This is an observational study, not a treatment trial. It may not directly improve memory, and results from brain recordings may not translate into practical surgical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 620 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2024

Expected to finish

Jun 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * For Aims I and III: Diagnosis of focal epilepsy or temporal lobe lesion; patients undergoing evaluation for or having undergone epilepsy surgery * For Aim II: Healthy adult participants * Full-Scale IQ ≥ 70 * English proficiency sufficient to understand and complete the task * For Aim I: Enrolled in or eligible for Emory University epilepsy surgery research registry * For Aim III: Undergoing clinically indicated stereoelectroencephalography (SEEG) at UC Davis Medical Center * Able to provide informed consent (or for Aim I retrospective component, prior consent in Emory registry) Exclusion Criteria: * Full-Scale IQ \< 70 * Inability to provide informed consent * For Aim III: Age \> 55 years * For Aim II: History of neurological or psychiatric disorder (as applicable per study protocol)

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Conditions

The condition(s) this trial relates to.

cognitive disorder Drug Resistant Epilepsy epilepsy focal epilepsy Memory Disorders Orientation, Spatial temporal lobe epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • UC Davis Medical Center

    RECRUITING

    Sacramento, California, 95817, United States

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