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New Triple-Drug cocktail targets tough cancers

NCT ID NCT04495257

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 25 times

Summary

This early-phase study tests a new drug (APX005M) combined with two existing immunotherapy drugs (nivolumab and ipilimumab) in people with advanced melanoma or kidney cancer who haven't had prior immunotherapy. The main goals are to check safety and find the best dose. About 26 adults will participate, and they must have a tumor that can be biopsied.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Yale Cancer Center

    New Haven, Connecticut, 06519, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.