Meditation may reshape your brain, new scan study hints
NCT ID NCT05418608
First seen Jun 10, 2026 · Last updated Jun 19, 2026 · Updated 2 times
Summary
This study used PET scans to compare the density of synapses—connections between brain cells—in 40 people: experienced meditators and non-meditators. Researchers gave participants a radioactive tracer that binds to a protein on synapses, then scanned their brains. The goal was to see if long-term meditation is linked to differences in brain structure.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Yale University PET Center
New Haven, Connecticut, 06519, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
[11C]UCB-J (a radioactive tracer for PET scans)
What this could lead to
If successful, this could reveal how meditation changes the brain at a microscopic level, pointing toward new ways to support mental health.
What could go wrong
This is a small, early-phase imaging study with only 40 participants, so results may not apply broadly. It measures brain activity, not health outcomes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.