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Live music may soothe Alzheimer's patients and caregivers, yale study hints

NCT ID NCT06940687

Symptom relief Sponsor: Yale University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This study from Yale University will test whether listening to live music can reduce anxiety and improve brain activity in people with early Alzheimer's disease, dementia, or mild cognitive impairment, along with their caregivers. Sixty pairs (patient and caregiver) will attend both a live concert and a recorded music session while researchers measure their heart rate, brain waves, and facial expressions. The goal is to see if live music offers unique benefits for emotional well-being and connection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Live music performance
What this could lead to
If it works, this could point toward a simple, drug-free way to ease anxiety and improve well-being for people with early Alzheimer's and their caregivers.
What could go wrong
This is a small, early-stage study with only 60 participants, so results may not apply to everyone. It measures brain activity and heart rate, not long-term disease changes, so benefits may be temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical Dementia Rating 0.5 - 2 * Be a person with or caregiver to a person with a diagnosis of early Alzheimer's Disease, mild dementia, and/or mild cognitive impairment (MCI) * Able to provide informed consent * Willing to wear an EEG headset and heart rate monitoring devices * Willing to possibly have small patches of body / facial hair shaved to accommodate administration of heart rate monitoring devices * Willing to answer survey questions about topics related to the study * Willing to be audio / video recorded Exclusion Criteria: * Clinical Dementia Rating \<0.5 or \> 2 * Unable to provide informed consent * Endorsing suicidal ideation (SI), self-injurious behavior, or homicidal ideation (HI) above the threshold defined in the "Risk Reduction and Safety Plan" * Participating in another clinical trial studying AD and/or Dementia * Starting a new prescription medication in the last 6 months * Prescribed Benzodiazepines on an as needed basis

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Conditions

The condition(s) this trial relates to.

Alzheimer disease anxiety disorder Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer disease Caregiver Dementia Mild cognitive impairment Peer-bonded caregiver

Contacts and locations

Locations

  • Firehouse 12 Studios

    New Haven, Connecticut, 06510, United States

  • Musical Intervention Studios

    New Haven, Connecticut, 06520, United States

More trials for these conditions

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