Can a common ADHD drug curb binge eating after bariatric surgery?
NCT ID NCT04599504
First seen Feb 04, 2026 · Last updated Jun 23, 2026 · Updated 17 times
Summary
This study tests whether the medication lisdexamfetamine (Vyvanse) can reduce loss-of-control eating and help with weight management in people who had bariatric surgery but still struggle with eating issues. About 60 adults who did not respond to earlier treatments will receive either the drug or a placebo daily for several months. The goal is to see if the medication leads to fewer binge episodes and better weight outcomes.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Yale School of Medicine
New Haven, Connecticut, 06519, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lisdexamfetamine (Vyvanse)
What this could lead to
If it works, this could provide a medication option for people who struggle with loss-of-control eating after bariatric surgery, helping them maintain weight loss.
What could go wrong
This is a small, early-stage trial (60 participants) and the medication may not work better than placebo. Side effects of lisdexamfetamine include increased heart rate, insomnia, and appetite suppression.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.