Tanabe Pharma Corporation

This study tested a booster dose of the DTaP vaccine (BK1301) in 446 adolescents aged 11-12 who had already received the vaccine series as children. The goal was to confirm the booster effectively strengthens immunity against diphtheria, tetanus, and pertussis (whooping cough). R…

This study tested a new vaccine called BK1310 in 370 healthy infants to see if it is safe and works well. The vaccine aims to protect against Hib, diphtheria, pertussis, tetanus, and polio. Researchers compared it to existing vaccines to check how well it triggers the immune syst…

This study tested a new vaccine called MT-2301 in 154 healthy infants to see if it protects against Haemophilus influenzae type b (Hib) disease. The vaccine was given along with routine childhood shots, and its effects were compared to an existing Hib vaccine. The goal was to che…

This study tested a drug called MCI-186 in 36 adults who had an acute ischemic stroke (a stroke caused by a blood clot). The main goal was to see if the drug is safe and how the body processes it. Participants received either the drug or a placebo within 1 to 24 hours after their…

This study tested whether ursodeoxycholic acid (UDCA) can improve liver health in people with chronic hepatitis C. About 600 adults in Japan took different doses of UDCA for 24 weeks. Researchers measured changes in liver enzymes to see if higher doses work better than a low dose…

This study tested whether adding teneligliptin to metformin helps Chinese adults with type 2 diabetes control their blood sugar better than metformin alone. 247 participants took either the combination or a placebo for 24 weeks. The main goal was to see changes in HbA1c, a key bl…

This study tested a new drug, MP-513 (Teneligliptin), added to a standard diabetes pill (pioglitazone) in 204 Japanese adults with type 2 diabetes. The goal was to see if the combination improved blood sugar control over 12 weeks, with a follow-up up to 52 weeks. Participants had…

This study looked at the safety of an oral form of edaravone for people with ALS. It was an extension of two earlier studies, and 15 people took part. Participants took the medicine for 10 days out of every 14-day cycle, followed by a 14-day break. The main goal was to track any …

This study tested whether adding canagliflozin to the existing drug teneligliptin helps Japanese adults with type 2 diabetes who still have high blood sugar. 138 participants took both drugs daily for 24 weeks. The main goal was to see if the combination improved HbA1c levels, a …

This study tested a medication called TA-7284 in over 1,200 Japanese adults with type 2 diabetes. The goal was to see if it is safe and helps control blood sugar over 52 weeks, either alone or with other diabetes drugs. Researchers tracked side effects, blood sugar levels, weight…

This study tested a drug called MCI-196 in 642 adults on dialysis who had high phosphorus and cholesterol levels. Participants took either the drug or a placebo for 12 weeks to see if it could safely lower these levels. The goal was to help manage heart and bone risks in people w…

This study tested whether increasing the dose of infliximab (a drug that blocks inflammation) helps people with active rheumatoid arthritis who were not helped enough by methotrexate alone. A total of 327 adults received three starting doses of infliximab, then were split into gr…

This study tested an experimental drug called MCI-196 in 183 adults with type 2 diabetes. Over 12 weeks, researchers measured how well it controlled blood sugar and checked for side effects. They also looked at its effect on cholesterol levels. The goal was to see if MCI-196 coul…

This study tested whether adding MP-435 to standard methotrexate treatment helps people with rheumatoid arthritis who did not get enough relief from methotrexate alone. Over 12 weeks, 112 participants received either MP-435 or a placebo. The main goal was to see if the combinatio…

This study tested a diabetes medication called teneligliptin in 254 Chinese adults with type 2 diabetes. Participants were randomly assigned to receive either teneligliptin or a placebo for 24 weeks. The main goal was to see if teneligliptin could lower blood sugar levels (HbA1c)…

This study tested a new drug called MP-424 combined with two standard hepatitis C medicines (peginterferon alfa-2b and ribavirin) in 10 people with genotype 2 hepatitis C who had not responded to earlier treatment. The goal was to see if the virus could be cleared from the blood …

This study tested three different doses of a blood thinner called argatroban, given with standard drugs (clopidogrel and aspirin), in 140 patients with stable coronary artery disease or unstable angina who needed a procedure to open blocked heart arteries. The goal was to see how…

This study tested a drug called MCI-186 in 137 people with ALS, a nerve disease that weakens muscles over time. The goal was to see if daily infusions could slow the disease's progress over 24 weeks. While the drug was safe, it only showed a small effect on slowing decline, meani…

This study tested a new drug called MP-513 in 99 Japanese adults with type 2 diabetes. The goal was to see how well it controls blood sugar over a full day after 4 weeks of treatment. Participants took the drug and had their blood sugar measured after meals and throughout the day…

This study tested an experimental pill called TA-7284 in 383 adults with type 2 diabetes. The goal was to see if it safely lowers blood sugar and helps with weight. Participants took either the drug or a placebo for several weeks. The results will help decide if larger studies ar…

This study tested a lower dose (0.6 mg/kg) of the clot-busting drug alteplase in 103 Japanese patients who had an ischemic stroke within the past 3 hours. The goal was to see if this dose was both safe and effective in reducing disability. Results focused on how many patients had…

This study looked at how well the drug argatroban works in 20 adults with a serious blood condition called heparin-induced thrombocytopenia Type II. These patients needed a blood thinner because their bodies reacted badly to the common drug heparin. The researchers tracked deaths…

This study tested a new drug called MP-214 in 512 people with schizophrenia who were having a flare-up of symptoms. The goal was to see if the drug reduces symptoms like hallucinations and delusions better than a placebo. Researchers measured symptom changes using standard rating…

This study tested whether adding canagliflozin (a diabetes pill) to insulin helps people with type 2 diabetes control their blood sugar better than insulin alone. About 146 adults with type 2 diabetes who were already on a stable insulin dose took either canagliflozin or a placeb…

This study tested a drug called TA-650 (also known as infliximab) in 18 people with Behcet's disease who had serious symptoms like ulcers or brain inflammation that didn't get better with standard treatments. The drug was given as an infusion at weeks 0, 2, and 6, then every 8 we…

This study tested a drug called TA-650 in 31 children with Kawasaki disease whose fever did not go away after standard IVIG treatment. The goal was to see if TA-650 could safely reduce fever and prevent heart artery damage better than another control drug. The trial is complete, …

This early-phase study tested an experimental drug called MP-424 in 15 people with chronic hepatitis C (genotype 1b) who had not taken interferon before. The main goal was to see if the drug could make the virus undetectable 24 weeks after treatment ended, and to check for side e…

This study tested whether a drug called AST-120, taken as a pill, could slow down chronic kidney disease in people with moderate to severe kidney problems. Over 1,000 adults participated, and researchers measured how long it took for patients to need dialysis, a kidney transplant…

This study looked at the long-term safety and effectiveness of adding canagliflozin to insulin treatment in 139 adults with type 2 diabetes. Participants had already completed a 16-week study and continued taking the combination for an extended period. Researchers tracked side ef…

This study tested a drug called AST-120 (a type of charcoal that absorbs toxins) in over 1,000 adults with moderate to severe chronic kidney disease. The goal was to see if adding AST-120 to standard care could delay the need for dialysis or a kidney transplant, or slow the rise …

This study tested a new medication called MP-214 in 34 adults with schizophrenia. Participants took the pill once daily for 14 days to see if it was safe and how well it worked. The goal was to find the right dose and check for side effects.

This early-stage study tested a single dose of MT-2990 in 75 adults with seasonal allergic rhinitis from Japanese cedar pollen. The goal was to check safety, how the drug moves through the body, and its effect on allergy symptoms in a controlled pollen exposure chamber. Participa…

This study tested a medicine called TAU-284 in 473 children aged 7 to 15 who have year-round allergic rhinitis (nasal allergies). The goal was to see if it works better than a placebo (a dummy pill) at reducing sneezing, runny nose, and stuffiness over two weeks. The medicine is …

This study tested a new drug called MP-214 in 38 people with schizophrenia over 12 weeks. The goal was to see how the drug moves through the body, if it is safe, and if it helps control symptoms. Participants had to have a schizophrenia diagnosis and be in generally good health o…

This study tested a new drug called MT-5547 in 626 people with moderate to severe pain from osteoarthritis of the knee or hip. The goal was to see if it reduces pain better than a placebo over 16 weeks. Researchers also checked how well it works and its safety with longer use.

This study tested an experimental drug called MT-8554 to see if it can safely reduce pain in people with nerve damage from diabetes. 156 adults with pain lasting at least 3 months received either the drug or a placebo. The main goal was to measure changes in average daily pain ov…

This study looked at how an experimental drug called MT-8554 changes the way the body processes two common cholesterol-lowering statins, simvastatin and rosuvastatin. Twenty-eight healthy men took the statins alone and then with MT-8554 to compare drug levels and safety. The goal…

This study tested whether MCI-186, an experimental drug, affects the heart's electrical activity (QT interval) in 27 healthy adult men. Participants received different doses of the drug and a placebo to compare effects. The goal was to check for any heart rhythm risks, not to tre…

This study looked at how colestilan, a drug for high phosphate levels in kidney disease, changes the way the body absorbs candesartan, a blood pressure medication. Eighteen healthy men took candesartan alone or at different times around colestilan doses. The goal was to see if ti…

This early-stage study looked at how a single dose of oral edaravone is processed by the body in 9 Japanese adults with ALS. The goal was to measure drug levels in blood and urine, not to test if it helps symptoms or slows the disease. Participants were aged 20-75 with definite o…

This early-stage study looked at how an oral form of edaravone interacts with other drugs (rosuvastatin, sildenafil, furosemide) in healthy adult males. It also compared how Japanese and Caucasian men process the drug. The goal was to gather safety and drug-level data, not to tre…

This study looked at whether an oral suspension (liquid taken by mouth) of edaravone works the same as the intravenous (IV) form given through a vein. It involved 42 healthy Japanese adults aged 20 to 45. The goal was to measure how much of the drug gets into the blood and how fa…