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New antipsychotic MP-214 tested in 512-Person trial

NCT ID NCT01625000

First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 28 times

Summary

This completed study tested an experimental drug called MP-214 in 512 adults with schizophrenia who were having a flare-up of symptoms. Participants took either a placebo, a standard antipsychotic (risperidone), or one of three doses of MP-214 daily for six weeks. The main goal was to see if MP-214 reduces symptoms like hallucinations and confusion better than placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Study site

    Sapporo, Hokkaido, Japan

  • Study site

    Seoul, South Korea

  • Study site

    Taipei, Taiwan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MP-214 (an experimental antipsychotic drug)

What this could lead to

If successful, MP-214 could offer a new daily medication option to help control schizophrenia symptoms like hallucinations and delusions.

What could go wrong

This is an early-to-mid stage trial; the drug may not work better than placebo or existing treatments. Side effects are possible, and long-term safety is not yet known.

Conditions

The condition(s) this trial relates to.

psychiatric disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.