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New drug MT-2990 tested in rare blood vessel disease

NCT ID NCT06196905

First seen Dec 16, 2025 · Last updated Jun 21, 2026 · Updated 30 times

Summary

This early study looked at a new drug, MT-2990, in 5 people with ANCA-associated vasculitis, a rare disease where the immune system attacks blood vessels. The goal was to see if the drug is safe and how it affects disease activity. Researchers measured changes in symptoms, imaging, and lab tests, but no single main outcome was set.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hiroshima University Hospital

    Hiroshima, Hiroshima, 734-8551, Japan

  • Juntendo University Hospital

    Bunkyo-ku, Tokyo, 113-8431, Japan

  • Kagawa University Hospital

    Kita-gun, Kagawa-ken, 761-0793, Japan

  • Keio University Hospital

    Shinjuku-ku, Tokyo, 160-8582, Japan

  • Kyorin University Hospital

    Mitaka-shi, Tokyo, 181-8611, Japan

  • NHO Tokyo Medical Center

    Meguro-ku, Tokyo, 152-8902, Japan

  • Saitama Medical Center

    Kawagoe, Saitama, 350-8550, Japan

  • Saitama Medical University Hospital

    Iruma-gun, Saitama, 350-0495, Japan

Conditions

The condition(s) this trial relates to.

anti-neutrophil cytoplasmic antibody-associated vasculitis eosinophilic granulomatosis with polyangiitis granulomatosis with polyangiitis microscopic polyangiitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.