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New diabetes pill shows promise in early trial

NCT ID NCT00628212

First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 27 times

Summary

This phase 2 study tested a new drug called teneligliptin (MP-513) in 324 Japanese adults with type 2 diabetes. Participants took one of three doses of the drug or a placebo daily for 12 weeks. The main goal was to see how well the drug lowered blood sugar levels (HbA1c) and to check for side effects. The results will help determine the right dose for larger, confirmatory studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Study site

    Takikawa-shi, Hokkaido, Japan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Teneligliptin (also called MP-513), a drug taken once daily to lower blood sugar

What this could lead to

If successful, this could provide a new once-daily pill option to help control blood sugar in people with type 2 diabetes.

What could go wrong

This is an early-phase trial with only 324 participants over 12 weeks. Long-term safety and effectiveness are not yet known, and results may not apply to non-Japanese populations.

Conditions

The condition(s) this trial relates to.

Insulin Resistance type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.