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Diabetes drug may slow kidney failure in high-risk patients

NCT ID NCT03436693

First seen Jan 09, 2026 · Last updated May 25, 2026 · Updated 28 times

Summary

This study tested whether canagliflozin, a diabetes medicine, can slow kidney damage in 308 Japanese adults with diabetic nephropathy (kidney disease caused by diabetes). Participants took either the drug or a placebo for 104 weeks. The main goal was to see if fewer people on the drug had a 30% drop in kidney function. The study also checked for safety and other kidney-related outcomes.

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Contacts and locations

Locations

  • Research site

    Shizuoka, Japan

  • Research site

    Tochigi, Japan

  • Research site

    Tokyo, Japan

  • Research site

    Wakayama, Japan

  • Research site

    Yamagata, Japan

  • Research site

    Yamaguchi, Japan

  • Research site

    Aichi, Japan

  • Research site

    Chiba, Japan

  • Research site

    Fukuoka, Japan

  • Research site

    Fukushima, Japan

  • Research site

    Gunma, Japan

  • Research site

    Hiroshima, Japan

  • Research site

    Hokkaido, Japan

  • Research site

    Hyōgo, Japan

  • Research site

    Ibaraki, Japan

  • Research site

    Kagawa, Japan

  • Research site

    Kagoshima, Japan

  • Research site

    Kanagawa, Japan

  • Research site

    Kumamoto, Japan

  • Research site

    Mie, Japan

  • Research site

    Nagano, Japan

  • Research site

    Nagasaki, Japan

  • Research site

    Okinawa, Japan

  • Research site

    Osaka, Japan

  • Research site

    Ōita, Japan

  • Research site

    Saitama, Japan

Conditions

Explore the condition pages connected to this study.