Diabetes kidney drug shows promise in slowing damage
NCT ID NCT03436693
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether canagliflozin, a diabetes drug, can slow kidney decline in 308 Japanese patients with diabetic nephropathy. Participants took either the drug or a placebo daily for about two years. The main goal was to see if fewer people on the drug had a 30% drop in kidney function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
canagliflozin
What this could lead to
If successful, this could provide a new option to slow kidney damage in people with diabetes-related kidney disease.
What could go wrong
This is a completed Phase 3 trial in Japanese patients only, so results may not apply to other populations. The drug may not significantly slow kidney decline compared to placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research site
Aichi, Japan
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Chiba, Japan
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Fukuoka, Japan
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Fukushima, Japan
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Gunma, Japan
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Hiroshima, Japan
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Hokkaido, Japan
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Hyōgo, Japan
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Ibaraki, Japan
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Kagawa, Japan
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Kagoshima, Japan
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Kanagawa, Japan
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Kumamoto, Japan
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Mie, Japan
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Nagano, Japan
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Nagasaki, Japan
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Okinawa, Japan
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Osaka, Japan
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Ōita, Japan
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Saitama, Japan
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Shizuoka, Japan
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Tochigi, Japan
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Tokyo, Japan
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Wakayama, Japan
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Yamagata, Japan
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Yamaguchi, Japan