Diabetes drug slows kidney decline in High-Risk patients
NCT ID NCT03436693
First seen Jan 09, 2026 · Last updated May 16, 2026 · Updated 26 times
Summary
This study tested whether canagliflozin, a diabetes medication, could protect kidney function in 308 Japanese adults with diabetic nephropathy (kidney damage from diabetes). Participants took either the drug or a placebo for 104 weeks. The main goal was to see if fewer people on canagliflozin had a 30% drop in kidney filtration rate. Results showed canagliflozin helped slow kidney decline, but patients still need ongoing diabetes and kidney management.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Research site
Aichi, Japan
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Chiba, Japan
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Fukuoka, Japan
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Fukushima, Japan
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Gunma, Japan
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Hiroshima, Japan
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Hokkaido, Japan
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Hyōgo, Japan
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Ibaraki, Japan
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Kagawa, Japan
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Kagoshima, Japan
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Kanagawa, Japan
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Kumamoto, Japan
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Mie, Japan
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Nagano, Japan
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Nagasaki, Japan
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Okinawa, Japan
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Osaka, Japan
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Ōita, Japan
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Saitama, Japan
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Shizuoka, Japan
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Tochigi, Japan
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Tokyo, Japan
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Wakayama, Japan
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Yamagata, Japan
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Yamaguchi, Japan
Conditions
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