Ancient herbal formula put to the test against diabetic kidney disease
NCT ID NCT07698223
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This trial investigates whether adding Naoxintong Capsule, a traditional Chinese medicine made from 16 herbal and animal ingredients, to standard therapy can slow the progression of diabetic nephropathy in people with type 2 diabetes. The study involves 410 participants who will receive either the capsule or a placebo for 12 months. The main goal is to measure the annual rate of kidney function decline, along with other kidney and heart health outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Naoxintong Capsule (a blend of 16 herbal and animal ingredients)
- What this could lead to
- If effective, this could offer a new add-on therapy to slow kidney decline and reduce cardiovascular risk in people with diabetic nephropathy.
- What could go wrong
- This is a Phase 4 trial with a moderate sample size. The herbal mixture is complex, and results may not generalize beyond the studied population. Side effects from the multiple ingredients are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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China-Japan Friendship Hospital
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chinese PLA General Hospital, First Medical Center
Beijing, Beijing Municipality, 100853, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Daping Hospital, Army Medical University
Chongqing, Chongqing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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First Affiliated Hospital of Dalian Medical University
Dalian, Liaoning, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhejiang Provincial Hospital of Traditional Chinese Medicine
Hangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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