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New daily pill MP-214 tested for Long-Term schizophrenia control

NCT ID NCT01625897

First seen Jan 07, 2026 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study tested the long-term safety and effectiveness of MP-214, a once-daily pill, in 125 people with chronic or elderly schizophrenia. Participants took a fixed dose for four weeks, then a flexible dose for the rest of the study. The goal was to see if MP-214 could help manage symptoms over time with an acceptable safety profile.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Study site

    Aizu-Wakamatsu, Fukushima, Japan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MP-214 (a daily pill) compared to risperidone

What this could lead to

If successful, MP-214 could offer a new daily medication option to help control schizophrenia symptoms over the long term.

What could go wrong

This is an early-to-mid-stage study with only 125 participants, so results may not apply to everyone. Side effects are possible, and the drug may not work better than existing treatments.

Conditions

The condition(s) this trial relates to.

psychiatric disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.