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Lower-Dose stroke drug shows promise in japanese trial

NCT ID NCT00147316

First seen Jan 11, 2026 · Last updated Jun 18, 2026 · Updated 23 times

Summary

This study tested a lower dose (0.6 mg/kg) of the clot-busting drug alteplase in 103 Japanese patients who had a stroke within the previous 3 hours. The goal was to see if this dose was both safe and effective for this population. Results focused on how many patients had little to no disability after 3 months and how many had bleeding in the brain as a side effect.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Cardiovascular Center

    Suita, Osaka, 565-8565, Japan

Conditions

The condition(s) this trial relates to.

brain ischemia cerebral infarction ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.