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New hope for kids with severe colitis: drug shows promise in small trial

NCT ID NCT01585155

First seen Jan 11, 2026 · Last updated Jun 17, 2026 · Updated 21 times

Summary

This study tested a drug called TA-650 in 21 children with moderate to severe ulcerative colitis, a condition causing inflammation and sores in the colon. The goal was to see if the drug could reduce disease activity and improve symptoms. Children received the drug by infusion at several time points over 22 weeks, and doctors measured changes using a clinical activity index. The study focused on controlling the disease rather than curing it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Investigational site

    Chūbu, Japan

  • Investigational site

    Hokkaido, Japan

  • Investigational site

    Hokuriku, Japan

  • Investigational site

    Kanto, Japan

  • Investigational site

    Kinki, Japan

  • Investigational site

    Kyusyu, Japan

  • Investigational site

    Tōhoku, Japan

Conditions

The condition(s) this trial relates to.

inflammatory bowel disease 1 Pediatric ulcerative colitis ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.