New hope for kids with severe colitis: drug shows promise in small trial

NCT ID NCT01585155

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called TA-650 in 21 children with moderate to severe ulcerative colitis, a condition causing inflammation and sores in the colon. The goal was to see if the drug could reduce disease activity and improve symptoms. Children received the drug by infusion at several time points over 22 weeks, and doctors measured changes using a clinical activity index. The study focused on controlling the disease rather than curing it.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational site

    Chūbu, Japan

  • Investigational site

    Hokkaido, Japan

  • Investigational site

    Hokuriku, Japan

  • Investigational site

    Kanto, Japan

  • Investigational site

    Kinki, Japan

  • Investigational site

    Kyusyu, Japan

  • Investigational site

    Tōhoku, Japan

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Other studies related to the condition(s) this trial covers.