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New hope for kids with severe colitis: drug shows promise in small trial

NCT ID NCT01585155

Completed Disease control Sponsor: Tanabe Pharma Corporation Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated May 09, 2026 · Updated 14 times

Summary

This study tested a medicine called TA-650 (similar to infliximab) in 21 children with moderate to severe ulcerative colitis, a disease causing inflammation in the colon. The goal was to see if the drug could reduce symptoms and help children feel better. Children received the drug by IV at weeks 0, 2, 6, 14, and 22, and doctors measured disease activity using a scoring system. The study found that some children achieved remission, but because this is a lifelong condition requiring ongoing management, it is not a cure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Investigational site

    Chūbu, Japan

  • Investigational site

    Hokkaido, Japan

  • Investigational site

    Hokuriku, Japan

  • Investigational site

    Kanto, Japan

  • Investigational site

    Kinki, Japan

  • Investigational site

    Kyusyu, Japan

  • Investigational site

    Tōhoku, Japan

Conditions

Explore the condition pages connected to this study.

PEDIATRIC ULCERATIVE COLITIS PEDIATRIC ULCERATIVE COLITIS