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New combo therapy for arthritis shows promise in early trial

NCT ID NCT01143337

First seen Jan 08, 2026 · Last updated Jun 18, 2026 · Updated 29 times

Summary

This study tested whether adding MP-435 to standard methotrexate treatment helps people with rheumatoid arthritis who did not get enough relief from methotrexate alone. Over 12 weeks, researchers measured improvements in joint pain, swelling, and daily function. The trial involved 112 adults and was designed to check safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Investigational site

    Osaka, Japan

Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.