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Higher dose of Crohn's drug shows promise for tough cases

NCT ID NCT00805766

First seen Jan 09, 2026 · Last updated Jun 17, 2026 · Updated 18 times

Summary

This study looked at whether a higher dose (10 mg/kg) of the drug infliximab (TA-650) could help people with Crohn's disease who were not getting enough benefit from the standard dose (5 mg/kg). The 39 participants received the higher dose every 8 weeks. The main goal was to see if their symptoms, measured by a standard Crohn's disease activity index, improved significantly after 8 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Investigational site

    Hokkaido, Japan

  • Investigational site

    Kansai, Japan

  • Investigational site

    Kanto, Japan

  • Investigational site

    Kyushu, Japan

Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.