PREGNANCY

This study is testing if giving monthly cash payments to pregnant women with HIV in Botswana helps them manage their health better. Researchers want to see if the money reduces stress, helps women take their HIV medication consistently, and keeps them in care after giving birth. …

This study tests whether bacteria from a mother works better than store-bought probiotics to help C-section born babies develop healthy gut bacteria. Researchers will compare babies who receive these treatments to untreated C-section babies and vaginally born babies. Participants…

This pilot study is testing two practical strategies to help pregnant and postpartum people stay engaged in treatment for substance use disorder. The first strategy involves screening for basic needs like housing and transportation and connecting people to community support servi…

This study tests an online platform called MOVIN that provides mental health support to pregnant and postpartum people experiencing depression or anxiety. Participants work with a care coordinator through a website to create personalized treatment plans and track their progress. …

This study aims to see if teaching stress management techniques to pregnant women can lower their stress hormones and potentially reduce risks like preterm birth. Researchers will enroll 50 pregnant women who are at least 24 weeks along to track their stress levels and learn abou…

This study is testing a digital program designed to help pregnant women who have overweight or obesity manage their weight gain, activity, and eating habits. 144 participants will use smart scales and activity trackers while receiving weekly coaching, with the goal of staying wit…

This study is testing if an automated insulin delivery system (a wearable pump that adjusts insulin on its own) works better than the current standard of care (an insulin drip into a vein) for managing blood sugar during labor and delivery in pregnant people with type 1 diabetes.…

This study is testing whether adding a daily probiotic supplement to a special coenzyme Q10 toothpaste helps improve gum health in pregnant women. Forty participants will receive professional dental cleanings and will use either the toothpaste alone or the toothpaste plus probiot…

This study is testing a program to help low-income pregnant women quit smoking. It combines daily text message support with small financial rewards for staying smoke-free. Researchers want to see if this approach is practical and well-liked by participants, and if it helps them q…

This study is testing if a wearable continuous glucose monitor (CGM) is easier for pregnant women with type 2 diabetes to use than the standard finger-prick method. It will see if patients are better at tracking their blood sugar with the CGM, which could lead to better health fo…

This study is testing a new medical device called the OdonAssist™ to help with difficult vaginal births in a rural Ethiopian hospital. It aims to see if the device is safe, effective, and acceptable to use in a low-resource setting, and to compare its costs to current methods lik…

This study is testing whether a therapy program with a supporting mobile app can help pregnant people stay on their prescribed medication for opioid use disorder. It compares this app-based support to simply tracking medication use in a diary. The goal is to see which approach is…

This study is testing if using a surgical tourniquet during a specific operation for a serious childbirth complication called placenta accreta is safe for newborns. The main goal is to see if the technique affects the baby's first health check scores right after birth. Researcher…

This study is testing whether adding MRI scans to standard pregnancy ultrasounds can help doctors better detect and understand potential health problems in unborn babies. It will involve 1,500 pregnant participants who will receive a short, safe MRI scan. The goal is to see if MR…

This study is testing two new types of ultrasound imaging to see if they can better check the health of the placenta during pregnancy. Researchers will compare scans from 60 pregnant people—some with a condition where the baby is growing too slowly and some without—to see if the …

This study is testing a device called 'Enlighten' to see if it can accurately predict which pregnant women will develop postpartum depression (PPD) after giving birth. Researchers will enroll 1,000 pregnant women to collect blood and saliva samples during their third trimester an…

This study is testing a new portable device called VITA that aims to detect anemia and iron deficiency in pregnant women without needing a blood draw. Researchers will use the device to scan the ear's blood vessels and compare the results to standard blood tests from 300 particip…

This study aims to validate a new blood test designed to predict a woman's risk of developing postpartum depression. Up to 500 pregnant women will have a blood draw in their third trimester and then be followed for six months after giving birth to see if they develop depression. …

This project aims to improve health outcomes for pregnant people and their babies by connecting them with community health workers, doulas, and local services. It focuses on addressing social needs like safe housing, food security, and transportation that can affect pregnancy hea…

This study is testing whether specific types of exercise during pregnancy can improve health for overweight or obese mothers and lower the risk of obesity in their children. Researchers will enroll about 300 pregnant women and randomly assign them to different exercise programs o…

This study is testing if a city program that gives pregnant women free weekly baskets of organic, local vegetables can lower their exposure to pesticides. Researchers will compare the pesticide levels in the urine of women who receive the food baskets to those who continue their …

This study is testing whether a specific brand of prenatal vitamins (Perelel) works better than generic prenatal vitamins at improving nutrition and wellness during pregnancy. Researchers will enroll 600 pregnant women who will take one type of vitamin daily and have blood tests …

This study is testing a program called 'Sit Less, Move More' to help pregnant women reduce their sitting time and increase safe physical activity. Researchers will enroll 60 pregnant women to use a Fitbit, receive coaching, and exercise with a partner. The goal is to see if this …

This study compares three different support programs to help pregnant women maintain a healthy weight during pregnancy and after giving birth. Researchers want to see which approach works best at helping women return to their pre-pregnancy weight by 12 months after delivery. The …

This study is testing if finding and treating malaria very early in pregnancy can prevent serious problems for newborns. It will compare a new strategy—using a highly sensitive malaria test in the first three months of pregnancy—against standard prenatal care. The goal is to see …

This study is testing whether delivering healthy groceries to the homes of low-income pregnant women helps them gain a healthy amount of weight and eat better during pregnancy. Researchers will compare three groups: one receiving standard food assistance, one getting that food de…

This study aims to find the best way to give two important vaccines during pregnancy: one for RSV (a common respiratory virus) and one for whooping cough (Tdap). Researchers want to see if giving both shots at the same doctor's visit or at separate visits is more practical, safe,…

This study is testing whether a special oral care routine using lactoferrin (a protein found in milk) in both toothpaste and mouthwash is better than just the toothpaste at preventing gum disease in pregnant women. Forty pregnant women will be randomly assigned to use one of the …

This study is testing a new way to help pregnant women who struggle to afford enough healthy food. It will see if a flexible support system, offering different types of food assistance based on individual needs, is practical to run. The goal is to improve food security and health…

This study is testing whether a farming support program can prevent food scarcity and improve health for pregnant women and their babies in Kenya. The program provides seeds, irrigation pumps, training, and access to a demonstration farm. Researchers will enroll 410 pregnant wome…

This study is testing whether vitamin D supplements can prevent preeclampsia from recurring in pregnant women who had it in a previous pregnancy. Researchers will give 146 women either vitamin D pills or placebo pills and track who develops preeclampsia again. The goal is to find…

This study is comparing two medications, misoprostol and pitocin, to see which one is more effective at starting labor in pregnant patients with a body mass index (BMI) over 30. Researchers will measure how long it takes from the start of the induction process until the baby is d…

This small pilot study is testing a special exercise program designed for high-risk pregnant women who are on bed rest in the hospital. The program involves safe, supervised strength and resistance exercises that can be done while lying in bed. Researchers want to see if this pro…

This study is testing whether a small, wearable device that gently stimulates a nerve in the leg is a safe and practical way to manage restless legs syndrome (RLS) during pregnancy. Fifteen pregnant women will use the device at home for 8 weeks to see if it helps reduce their sym…

This study aims to improve the experience and recovery for women having a planned C-section. It compares sipping water against a carbohydrate-rich drink while waiting for surgery. Researchers will use ultrasound to check stomach safety and ask women to rate their recovery the nex…

This study is testing whether a special patch-like device can help reduce pain after a cesarean delivery, with the goal of helping women need less opioid pain medication. Researchers will compare the device to a fake version and to standard pain care in 180 women. The main thing …

This study is testing whether a 6-week mindfulness meditation program helps pregnant women feel less stressed, anxious, and depressed compared to a standard psychological support program. It will also see if the program improves bonding with their baby and leads to better infant …

This study aims to find the most effective starting dose of epidural medicine to relieve labor pain within the first 30 minutes. Researchers will test different amounts of a pain-relief mixture in 50 women in active labor to determine the dose that works for 90% of patients. The …

This study is testing whether a 12-week Baduanjin exercise program can help reduce low back and pelvic pain in pregnant women and improve their quality of life. Researchers will enroll 84 women who are 14-20 weeks pregnant and randomly assign them to either do the exercises or re…

This study is testing whether a specially designed fortified milk drink for pregnant and breastfeeding women improves the nutrient content of their breast milk and their own nutritional status. Researchers will compare levels of vitamins and minerals in the breast milk and blood …

This study aims to develop a prediction tool to identify which pregnant women with aplastic anemia are at highest risk for serious complications. It will observe 300 participants to collect data on their health and pregnancy outcomes. The goal is to help doctors make earlier, bet…

This study aims to see if blood pressure can be accurately measured at the ankle instead of the arm during planned C-sections. The goal is to determine if using an ankle cuff frees up the mother's arms, making it easier and more comfortable to hold her newborn for important skin-…

This study aims to understand how a pregnant person's immune system adapts to support a healthy pregnancy and prevent complications like miscarriage. Researchers will analyze blood samples from 100 women undergoing IVF treatment, collecting samples before pregnancy and during ear…

This study aims to understand if mothers who are well-informed about their upcoming labor induction have a better experience of childbirth. Researchers will also look at how using social media might influence that experience. The study involves 50 pregnant people who are schedule…

This study aims to understand the two-way relationship between pregnancy and inflammatory bowel diseases (IBD) like Crohn's and ulcerative colitis. Researchers will follow 945 women from a health registry to track how often their IBD symptoms flare up during pregnancy and after g…

This study aims to understand how antipsychotic medications affect pregnant women with serious mental illness and their babies. Researchers will follow 200 pregnant women who are either taking antipsychotics, other psychiatric medications, or no medication. They'll track the moth…

This study is exploring whether providing pasteurized donor human milk to infants born to mothers with HIV is a practical feeding option. Researchers will give donor milk to 10 families in Saskatchewan for 6-8 weeks and track how often it's used and any challenges. The goal is to…

This study aims to understand how two common antibiotics, ceftriaxone and benzathine penicillin G, move through the bodies of pregnant women and to check for any safety issues. Researchers will enroll about 78 pregnant women in the U.S. who are already receiving one of these anti…

This study aims to understand why American Indian women in the Midwest experience higher rates of poor birth outcomes. Researchers will gather information from 80 pregnant American Indian women about their experiences with historical trauma and current stress, while also measurin…

This study aims to understand if drinking water before a planned C-section affects stomach fluid volume differently in pregnant women with diabetes compared to those without. Researchers will use ultrasound to measure stomach volume in 70 women after they drink water, following s…

This study is testing how easy and useful a new digital weight management program is for pregnant women and new mothers. Up to 30 pregnant women with obesity will try the program for a week and then give feedback in an interview. The goal is to improve the program's design before…

This study aims to understand how restricted growth during pregnancy affects babies' long-term health. Researchers will follow 200 babies who are smaller than expected during pregnancy, using advanced ultrasound and MRI scans to monitor their brain, heart, and development. The go…

This study aims to understand the long-term health of children born to mothers who have had a solid organ transplant (like kidney, liver, or heart). Researchers want to see if these children have a higher risk of heart, kidney, or immune system problems later in life, possibly du…

This study aims to find the best time to discuss the possibility of a cesarean delivery (C-section) with pregnant patients planning a vaginal birth. Researchers will randomly assign 200 participants to have this consent conversation either when they are admitted to the hospital o…

This study aims to better understand how a common virus called parvovirus B19 affects pregnant women and their babies. Researchers will observe 150 pregnant women who have the infection to learn how often it passes to the fetus and what complications can occur. The goal is to gat…

This study is testing whether an artificial intelligence (AI) tool can rank embryos for IVF as effectively as a trained embryologist. About 1,325 women undergoing IVF will have their frozen embryos ranked either by the AI or by an embryologist. The main goal is to see if both met…

This study aims to understand if doing prenatal Pilates is linked to better sexual function and less sexual distress during pregnancy. Researchers will follow 120 pregnant women, comparing those who choose to do Pilates with those who don't do structured exercise. The study will …

This study aims to understand if tiny plastic particles in our environment affect gut bacteria and inflammation, potentially increasing the risk for Crohn's disease and other bowel conditions. Researchers will analyze stool samples from pregnant women with Crohn's, healthy women,…

This study aims to understand how pregnancy and breastfeeding affect long-acting injectable antipsychotic medications used for conditions like schizophrenia. Researchers will measure drug levels in the blood of pregnant and breastfeeding women, and also check how much of the medi…

This study aims to test new MRI technology designed specifically for pregnant women to get better quality images of babies in the womb. Researchers will compare these new MRI images against standard ultrasound and current MRI pictures. The study involves 300 pregnant women, inclu…

This study aims to understand how obesity before pregnancy might affect blood flow and oxygen delivery through the placenta. Researchers will use MRI scans in the second and third trimesters to compare these factors in women with obesity versus those with a normal weight. The goa…

This study aims to learn more about hemophilia A by following mother-child pairs from pregnancy through the child's early years. Researchers want to understand why some mothers with severe hemophilia have dangerous bleeding after childbirth and why some children develop antibodie…

This study aims to compare how two different forms of prenatal vitamins—a capsule and a gummy—affect nutrient levels in pregnant women. Researchers will measure changes in iron and other key nutrients in the blood of 40 healthy women during their second trimester after taking one…

This study aims to understand how pregnant people at risk for preeclampsia process aspirin and how that relates to their metabolic health. Researchers will enroll 50 participants who are already recommended to take aspirin for prevention. The study involves blood tests, urine col…

This Oxford University study aims to understand how tiny particles released by the placenta contribute to serious pregnancy complications like pre-eclampsia and gestational diabetes. Researchers will collect samples from 360 women, including those with healthy pregnancies and tho…

This study aims to understand what most influences excessive weight gain during pregnancy: physical activity, diet, or anxiety. Researchers will observe 150 women in their third trimester, collecting information through questionnaires and interviews. The goal is to identify which…

This study aims to find out how well pregnant women absorb iron from different types of prenatal supplements. Researchers will test 50 pregnant women in Kenya to see if taking supplements with food or on an empty stomach makes a difference, and if taking them every other day is m…

This study aims to collect placenta and blood samples from 1,250 women during delivery to create a research bank. Researchers will use these samples to learn how the placenta works in both healthy pregnancies and those with complications like preterm birth or diabetes. The goal i…

This study aims to understand why pregnant women living at high altitudes have higher rates of fetal growth restriction and preeclampsia. Researchers will compare tissue samples from women giving birth in Denver versus Summit County, Colorado, to see if altitude affects blood ves…

This study aims to understand how quickly water and a carbohydrate sports drink empty from the stomach of women in early labor. Researchers will compare women who have an epidural for pain relief to those who do not, using ultrasound to measure stomach volume over time. The goal …

This study aims to understand how blood clot formation changes during pregnancy and whether these changes can predict serious complications like high blood pressure disorders or dangerous blood clots. Researchers will compare 100 pregnant women with and without complications, mea…

This study aims to understand the safety of the epilepsy medication Epidiolex during pregnancy. Researchers will follow about 50 women who took the drug while pregnant and monitor their babies' health for the first year of life. The goal is to collect information on birth outcome…

This study aims to understand how exercise during and after pregnancy might change the makeup of breast milk. Researchers will measure the activity levels of 200 mothers, analyze their milk, and track their babies' growth and energy use. The goal is to learn if these changes in m…

This study aims to understand how pregnancy and early parenthood affect women with cystic fibrosis (CF) and how their children develop in early life. Researchers will observe 60 participants across three groups: women planning pregnancy or pregnant, their infants up to age 2, and…

This study is creating a large collection of biological samples and health information from up to 1,000 pregnant and postpartum people. The goal is to build a secure research resource, or 'biobank,' to help scientists better understand pregnancy complications and outcomes in the …

This study aims to better understand how gestational diabetes (high blood sugar during pregnancy) affects the health of both mothers and their babies over time. Researchers will follow 400 women diagnosed with this condition, collecting health information and samples during pregn…

This study is collecting body samples like stool, saliva, and blood from 600 people to build a library for future research. The goal is to help scientists understand how the trillions of microbes living in and on our bodies affect our health and contribute to diseases. Participan…

This study aims to collect safety information on pregnant and breastfeeding women with Pompe disease who are taking the medication Nexviazyme (avalglucosidase alfa). Researchers will follow the women and their babies for up to 10 years to check for any pregnancy complications or …

This study aims to understand the earliest communication between a mother and a newly formed embryo. Researchers are following healthy women trying to get pregnant, collecting daily samples like saliva and blood to see how the body signals change. By comparing cycles that lead to…

This study aims to understand why spinal anesthesia, commonly used for C-sections, can work differently from person to person. Researchers will observe 107 pregnant women having planned C-sections to see if their belly size and internal pressure affect how well the spinal block n…

This study aims to understand if Cambodia's health system is ready to provide a new, more comprehensive prenatal vitamin supplement to pregnant women nationwide. Researchers will interview healthcare workers, pregnant women, and government officials, and check supply chains in on…

This study is testing whether a smartphone app called 'HappyMums' can help researchers learn more about depression during pregnancy. It will enroll 1,000 pregnant people who are at risk for or currently experiencing depression. The app collects data through activities, questionna…

This study is testing whether support from a doula—a trained birth companion—can improve mental health and wellness for pregnant people. Researchers will enroll 75 pregnant participants from rural Montana to compare different types of doula care to standard care. The main goal is…

This study aims to gather information on the safety of the drug Ultomiris (ravulizumab) during pregnancy and breastfeeding. It will follow about 75 women who have rare conditions like PNH or aHUS and who took Ultomiris while pregnant. Researchers will track the health of both the…