New study tracks health of moms with CF and their infants
NCT ID NCT06797206
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 60 women with cystic fibrosis (CF) who are planning a pregnancy, pregnant, or new parents, along with their babies. Researchers will track lung function, nutrition, mental health, and pregnancy outcomes, as well as infant health issues like liver function and lung clearance. The goal is to understand what extra care or screening might be needed for these families.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better clinical guidelines for managing pregnancy and early parenthood in women with cystic fibrosis.
- What could go wrong
- This is an observational study, not testing a new treatment. It may not produce clear answers due to its small size (60 participants) and single-center design.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
1. Females aged 16 years or older with CF under the care of the Royal Brompton Hospital adult CF Unit who are planning a pregnancy or pregnant. 2. Biological offspring of people with CF (both mothers and fathers) cared for by the Royal Brompton Hospital Adult CF Service, from birth to aged six years.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 'Mama' sub-study: * Written informed consent obtained from participant. * Under the care of Royal Brompton Hospital CF Reproductive and Maternal Health Service * Age 16 years or above at time of recruitment * Confirmed diagnosis of CF * Planning a pregnancy or pregnant at time of recruitment. * Ability to adhere to the required visits and investigations. 'Mini' sub-study: * Written informed consent obtained from participant's legal guardian. * Infants who have one biological parent with a confirmed diagnosis of CF under care of Royal Brompton Hospital Adult CF Service * Less than 12 months of age at first visit. * Ability to adhere to the required visits and investigations. 'Midi' sub-study: * Written informed consent obtained from participant's legal guardian. * Children who have one biological parent with a confirmed diagnosis of CF who is under the care of Royal Brompton Hospital Adult CF Service. * Age three to six years at time of visit * Ability to adhere to the required visits and investigations. Exclusion Criteria: 'Mama' sub-study: * Any significant health condition which would cause inability to comply with protocol based on investigator discretion. * History of lung transplantation 'Mini' sub-study: * Legal guardians' inability to provide consent to participate in the study. * Mother of infant has significant comorbidities unrelated to CF which could affect infant outcomes based on investigator discretion. 'Midi' sub-study: * Legal guardians' inability to provide consent to participate in the study. * A significant health condition which is known to affect lung function or imaging based on investigator discretion
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Royal Brompton Hospital
RECRUITINGLondon, United Kingdom
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