PREGNANCY

This study tests whether a simple, balanced meal made from local foods, eaten once a day during pregnancy, can help women in rural Pakistan handle heat stress and have healthier babies. About 292 women planning to conceive will either eat this meal daily or continue their usual d…

This study compares two types of noninvasive dental care for 160 pregnant people with gum disease. Participants get free dental check-ups, cleanings, and supplies. The goal is to see which approach better reduces gum inflammation and improves oral health habits and birth outcomes…

This study checks how well a new home pregnancy test works. About 180 women will use the test and answer questions. Their results will be compared to lab tests to see if the test is easy to use and accurate.

This study will check if a simple finger prick blood test gives the same pregnancy hormone (beta-hCG) results as a standard blood draw from the arm. About 40 pregnant women will provide both types of blood samples so doctors can compare the numbers. If finger stick blood works ju…

This study tests different combinations of an online program called CARRII to help Native women reduce their risk of alcohol-exposed pregnancy. About 512 participants will be randomly assigned to one of eight groups to find the most effective and affordable approach. The goal is …

This study tests a counseling program called Healthy Families-PrEP that helps women in rural Uganda use HIV prevention medicine (PrEP) while trying to get pregnant, during pregnancy, and after giving birth. About 660 women who are HIV-negative but at risk will take part. The goal…

This study tests a personalized support program (PTBCARE+) for pregnant individuals at high risk of delivering early. The program includes stress-reduction tools, a website/app, and extra support during clinic visits. Researchers will compare stress levels and birth outcomes betw…

This study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during routine prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not part of standard pregnancy care. The study will enroll 6…

This study tests whether teaching women about healthy eating, activity, and other lifestyle habits before or during early pregnancy can improve their heart health and lower the chance of problems like gestational diabetes and preeclampsia. Two hundred women at risk for these issu…

This study compares how well women stick to a single daily pill that prevents both HIV and pregnancy versus taking two separate pills. About 300 women without HIV, aged 16-39, will try both methods in a crossover design. The goal is to see if a combined pill makes it easier to st…

This study compares two pain relief methods after a planned C-section: a small dose of morphine given with the spinal anesthetic, versus a numbing injection into the belly wall (TAP block). About 100 women will take part to see which approach provides better pain control with few…

This study will test whether virtual doula services—support via video calls—can improve birth outcomes and satisfaction for first-time mothers living in rural areas. About 614 pregnant women in their second or early third trimester will be randomly assigned to receive virtual dou…

This study looks at whether a mindfulness-based stress reduction program can help first-time pregnant women feel less anxious, worry less about their baby's health, and improve their overall mental well-being. About 100 women between 12 and 28 weeks of pregnancy will take part in…

This study looks at whether pregnant women with type 1 or type 2 diabetes can safely keep using their insulin pump during labor instead of switching to IV insulin. About 30 women who already use an insulin pump will be allowed to continue using it while giving birth. The goal is …

This study looks at whether eating milk chocolate during labor can shorten the pushing stage (second stage) for healthy pregnant women. Researchers will give 50 grams of milk chocolate to some women when their cervix is 6 cm dilated and compare their labor duration to women who d…

This study tests an online program called STORK that helps couples expecting their first baby navigate changes in their sexual relationship during pregnancy and after birth. The program provides information and skills to improve sexual satisfaction, desire, and reduce distress. A…

This study looks at whether using a small injection port on the skin helps pregnant women with diabetes take their insulin more regularly and feel better about their treatment. The port allows insulin to be given through the same spot without repeated needle sticks. Researchers w…

This study looks at whether a 10% lidocaine spray can make getting an IV less painful for women having a planned C-section. About 150 participants will either get the spray or a placebo before the IV is placed. They will then rate their pain on a scale from 0 to 10. The goal is t…

This study looks at whether using a weighted blanket can reduce nighttime leg cramps, improve sleep quality, and lower anxiety and stress in pregnant women. Fifty women in their third trimester will use the blanket for 14 days and compare results to a 14-day period without it. Th…

This study tests a short education program for first-time pregnant women to reduce fear of childbirth and stress. About 72 women in their third trimester will either take the program or get standard care. The goal is to help them feel more confident about a normal vaginal birth a…

This study will test if using absorbable staples under the skin can make C-section surgery faster and improve how the scar looks. About 237 women having a C-section will be randomly assigned to get either the new staples or standard stitches. Researchers will measure surgery time…

This study tests whether a weekly exercise program, plus extra pelvic floor therapy if needed, can reduce pelvic girdle pain in pregnant women. About 40 women with pelvic pain will either join the exercise group or receive standard care with a physical activity leaflet. Researche…

This study tests whether short weekly exercises delivered through a mobile app can help first-time parents manage their emotions and stress during pregnancy. Expecting mothers and fathers in Singapore will use the app, wear a Fitbit, and complete surveys about their well-being an…

This study tests a 4-week virtual reality program designed to help first-time pregnant women feel more confident and less anxious about childbirth. Sixty-eight women will be randomly assigned to use the VR tool or receive standard care. The goal is to see if VR can improve birth …

This study follows 120 women with twin pregnancies and their 240 babies for one year after birth. Researchers will measure air pollution, diet, lifestyle, and chemical exposures to see how these factors affect birth weight and early development. No treatments or medications are g…

This study tests whether AI-powered portable ultrasound devices can help frontline health workers detect pregnancy complications early in rural Ethiopia, where access to standard ultrasound is very limited. About 1,059 pregnant women will be split into three groups: two using dif…

This study looks at how sleep, activity, and meal timing in early pregnancy affect blood sugar patterns and the risk of gestational diabetes. About 140 pregnant women without diabetes will wear monitors and use a food app to track their habits. The goal is to see if these behavio…

This study tests whether listening to binaural beats (a type of sound therapy) can lower the amount of anxiety medication needed during a C-section done under spinal anesthesia. Researchers will compare two groups of pregnant women: one that listens to binaural beats and one that…

This study looks at how pregnant women's online health searches (cyberchondria) relate to their anxiety levels and how they view their own health. Researchers will survey 80 pregnant women using three questionnaires. No treatment or intervention is given—the goal is simply to und…

This study looks at how cystic fibrosis medications (CFTR modulators) change in the body during pregnancy and after childbirth. Researchers will measure drug levels in the blood, breast milk, and umbilical cord blood of 30 women. The goal is to understand how these drugs behave i…

This study looks at how to find tuberculosis (TB) in pregnant and postpartum women in Guinea-Bissau. Researchers will test new screening methods, including a symptom checklist, stool tests, and AI-powered chest X-rays, to see if they work better than current approaches. About 720…

This pilot study tests whether a brief educational session about safe exercise during pregnancy can improve women's knowledge, confidence, and physical activity levels. Thirty pregnant women with low-risk pregnancies will be randomly assigned to receive either standard prenatal c…

This study works with people who have Primary Ciliary Dyskinesia (PCD) and their doctors to create easy-to-understand resources about fertility and pregnancy safety. About 30 participants will help design and test these materials. The goal is to improve knowledge and support, not…

This study looks at a natural chemical called kynurenine in pregnant women with and without chronic kidney disease. Researchers want to see if low levels of this chemical are linked to preeclampsia, a dangerous condition that can harm mothers and babies. About 200 women will give…

This study looks at whether training healthcare providers can help pregnant patients get more support at work, like time off or schedule changes. About 400 pregnant women and their doctors will take part. The goal is to see if this training leads to better job protections and hea…

This study checks how often pregnant women who have their water break early carry a type of antibiotic-resistant bacteria called ESBL-producing Enterobacteriaceae. Researchers will follow 250 women in French hospitals, taking samples to track the bacteria over time. The goal is t…

This study aims to learn about the reproductive health experiences of female members and veterans of the Canadian Armed Forces. Researchers will survey over 1,000 women and interview about 30 individuals to understand issues like contraception, pregnancy, infertility, and pelvic …

This study follows 376 pregnant women from 36 weeks of pregnancy to 12 weeks after birth. Researchers will measure hip, back, belly, and pelvic floor muscles to see if they are linked to how a baby is delivered (vaginal or C-section) and to problems like incontinence or pelvic pa…

This observational study follows 111 children born to women with multiple sclerosis who received rituximab or similar drugs before or during pregnancy. Researchers want to see if the drug affects the baby's immune cells, increases infections, or weakens vaccine responses in the f…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant women before they receive anesthesia during delivery. About 250 first-time mothers will take part. The goal is to see if the quality of the check-up is similar an…

This observational study at Stanford will test if a noninvasive finger monitor can predict how pregnant women, including those with severe preeclampsia, respond to fluids. Researchers will compare the finger device's accuracy to standard heart ultrasound. The goal is to find a si…

This study looks at how doctors trust artificial intelligence (AI) when estimating a baby's weight during pregnancy. About 308 clinicians will review ultrasound cases and compare AI-based estimates with traditional methods. Some doctors will also see how certain the AI is about i…

This study will test if a mobile app called MI MOM helps improve pregnancy and postpartum health. About 500 pregnant women on Medicaid will either use the app or receive standard care. The app provides health information, text messages, and optional support from a community healt…

This study tests whether a real-time AI dashboard can help doctors make better decisions during labor for first-time mothers. About 400 women will be randomly assigned to have their care guided by the AI tool or to receive standard care. The main goal is to see if the AI can safe…