PREGNANCY

This study compares a technology-enhanced therapy program (including a mobile app) to standard medication monitoring for pregnant people taking buprenorphine for opioid use disorder. About 37 participants will be randomly assigned to either four therapy sessions plus app access o…

This study tests a digital platform that helps pregnant women with overweight or obesity manage their weight gain. 144 women will use the platform, track their weight and activity, and meet weekly with a dietitian. The goal is to see if the tool helps them stay within healthy wei…

This study looks at whether using a tourniquet during surgery for placenta accreta (a condition where the placenta doesn't detach after birth) can improve the health of newborns, measured by the Apgar score. About 100 pregnant women aged 20-40 with a single baby and prior C-secti…

This study looks at whether a fortified milk product, Super Mil Mamá, can improve the nutrient content of breast milk in pregnant and lactating women from vulnerable communities. Researchers will compare the levels of key nutrients like DHA, vitamins, and minerals in the breast m…

This study tests whether a Fitbit plus personalized coaching can help pregnant women who are not very active increase their physical activity and reduce sitting time. Researchers will enroll 60 women early in pregnancy and track their activity levels at several points. The goal i…

This study tests whether taking coenzyme Q10 (in toothpaste) and probiotics (as a daily supplement) can improve gum health in pregnant women who also receive regular dental cleanings. Forty pregnant women will be split into two groups: one gets the Q10 toothpaste plus probiotics,…

This pilot study looks at two ways to help pregnant and postpartum people with substance use disorder stay in treatment. One approach screens for social needs like housing or childcare and connects patients to community help. The other uses small rewards to encourage recovery-sup…

This study tests whether giving pregnant women in Kenya farming supplies, training, and access to a demonstration farm can improve their health and their baby's health. 410 pregnant women, half living with HIV, will be randomly assigned to receive the program right away or after …

This pilot study is testing whether eating fermented poi every day can improve the gut health of pregnant women and lower their risk of developing gestational diabetes. Fifty pregnant women between 10 and 24 weeks will eat one pound of poi daily for four weeks and receive nutriti…

This study looks at whether giving pregnant women free organic vegetables and teaching them about healthy eating can lower their exposure to pesticides. About 210 pregnant women in Strasbourg will take part. Researchers will measure pesticide levels in urine to see if the program…

This study tests whether using a toothpaste and mouthwash made with lactoferrin (a natural protein) can prevent gum disease in pregnant women. Forty pregnant women in their second trimester will either use both the toothpaste and mouthwash, or just the toothpaste, along with regu…

This study looks at whether different types of exercise (aerobic, resistance, or both) during pregnancy can lower the risk of obesity in children. Researchers will follow 300 overweight or obese pregnant women and their babies for one year after birth. The goal is to find the bes…

This study tests whether a single dose of cabergoline can prevent breast symptoms like pain, swelling, and milk leakage after abortion or pregnancy loss between 12 and 18 weeks. About 348 participants will receive either cabergoline or a placebo one hour after the procedure and r…

This study tests a device called NeuroCuple™, which uses no medication, to manage pain after cesarean delivery. Researchers will compare it to a sham device and standard care in 180 women. The goal is to see if it reduces pain and the need for opioid painkillers.

This pilot study explores whether a gentle strength and resistance exercise program done in bed can improve the physical and emotional well-being of high-risk pregnant women who are on bed rest in the hospital. About 20 participants will either follow the exercise program or rece…

This study looks at whether a 6-week mindfulness meditation program can help pregnant women feel less stressed, anxious, or depressed, and improve their bond with their baby. About 70 pregnant women will either join the meditation program or receive standard psychological support…

This study tests two common labor-inducing drugs, misoprostol and pitocin, in 300 pregnant people with a BMI of 30 or higher. The goal is to see which drug, when used with a foley catheter, leads to a faster delivery. Results will help doctors choose the best option for this grou…

This study compares an AI tool (iDAScore) to manual ranking by embryologists for selecting which frozen embryo to transfer first in IVF. About 1,325 patients will be randomly assigned to either AI or human ranking. The goal is to see if the number of transfers needed to achieve p…

This study is testing whether having groceries delivered to their homes can help low-income pregnant young women gain a healthy amount of weight and eat better. About 570 women in early pregnancy will take part. The goal is to learn if this simple support can make a difference an…

This study looks at whether Cambodia's health system is ready to give pregnant women a multiple micronutrient supplement (MMS) instead of just iron and folic acid. Researchers will interview healthcare workers, survey 630 pregnant women, and monitor vitamin supplies. The goal is …

This study aims to improve pregnancy and birth outcomes for all people in Rhode Island, especially those from minority and vulnerable groups. It brings together hospitals, community health workers, doulas, and local organizations to provide extra support like care coordination an…

This study looks at the long-term health of children (age 16 and older) whose mothers had a solid organ transplant before pregnancy. Researchers want to see if these children have higher risks for heart or kidney problems, possibly due to the mother's anti-rejection medicines. Ab…

This study looks at whether doulas with special training in perinatal mental health can help pregnant women in rural Montana feel more confident and supported, and reduce depression and anxiety. About 75 pregnant women will be split into three groups: one gets a specially trained…

This study looks at whether microplastics in the body can worsen gut inflammation and change the gut microbiome, especially in pregnant women with Crohn's disease. Researchers will measure microplastics in stool samples and analyze gut bacteria. The goal is to understand how envi…

This study looks at how drinking clear water two hours before a planned C-section affects stomach fluid in pregnant women with and without diabetes. Researchers will use ultrasound to measure stomach volume before and after drinking. The goal is to better understand aspiration ri…

This study follows healthy women who are trying to get pregnant, as well as women who are not, to collect samples and learn about the molecular signals between mother and embryo during the first two weeks after fertilization. The goal is to better understand what leads to a healt…

This study looks at how the information given to mothers about labor induction affects their childbirth experience. Researchers will also examine if social media plays a role. The study involves 50 pregnant women who are scheduled for labor induction. The goal is to understand ho…

This study tests whether pasteurized donor human milk (PDHM) is a practical feeding option for infants exposed to HIV. Ten caregivers in Saskatchewan will try PDHM as a supplement to breastfeeding or formula and report any challenges. The goal is to learn if donor milk can be off…

This study looks at the best time to get a patient's consent for a possible C-section. Some hospitals ask everyone when they arrive, while others wait until it seems needed. Researchers will compare these two approaches in 200 pregnant people to see which leads to a better experi…

This study uses special MRI scans to measure oxygen and blood flow in the placenta during pregnancy. Researchers want to see if these measurements differ between women with obesity and women with a healthy weight before pregnancy. The goal is to better understand why some pregnan…

This study follows 200 pregnant women with severe mental illness to see how taking antipsychotic medication affects their psychiatric health and their baby's development. Researchers will compare outcomes among women taking antipsychotics, other psychiatric drugs, or no medicatio…

This study collects daily urine samples from 1,500 women who are trying to conceive. Participants use a Clearblue ovulation test to track their fertile window and provide samples for up to 3 menstrual cycles. The samples are stored in a biobank for future research on pregnancy an…

This study follows 400 pregnant women diagnosed with gestational diabetes to learn how the condition affects both mother and baby during pregnancy and after birth. Researchers will collect health data and samples from mothers and infants at several points, including after deliver…

This study looks at how exercise and physical activity during and after pregnancy change the makeup of breast milk. Researchers want to see if these changes affect how babies use energy and grow, which could help prevent childhood obesity. The study will follow 200 mothers and th…

This study is testing two new ultrasound methods to see if they can tell the difference between healthy pregnancies and those affected by fetal growth restriction (FGR), where the baby is smaller than expected. Researchers will compare these new scans in 60 pregnant women, some w…

This study is testing whether adding MRI scans to standard ultrasound can help doctors better see and diagnose birth defects in unborn babies. About 1500 pregnant women will get a fetal MRI to check if it provides clearer details than ultrasound alone. The goal is to improve how …

This study looks at how stress affects pregnant women and whether simple stress management techniques can help. Researchers will measure stress using saliva samples from 50 women who are at least 24 weeks pregnant. The goal is to understand how social factors and chronic stress i…

This study looks at how different arm positions change blood pressure readings in pregnant women. About 300 participants will have their blood pressure taken with their arm supported at heart level, on their lap, or hanging at their side. The goal is to find out which position gi…

This study looks at bone density in 100 pregnant women (ages 30-45) between weeks 35 and 41 of pregnancy. Half are carrying one baby, half are carrying twins. Researchers use a special ultrasound-like scan (REMS) and questionnaires to see if twin pregnancies cause greater bone lo…

This study looks at whether two simple calculations using heart rate and blood pressure, taken before surgery, can predict which women will have a dangerous drop in blood pressure after receiving spinal anesthesia for a planned C-section. About 300 women having elective C-section…

This study aims to create a prediction tool for pregnant women with aplastic anemia, a rare blood condition that raises risks for both mother and baby. Researchers will follow 300 women to identify factors that lead to complications like bleeding, preterm birth, or low birth weig…

This study looks at how the antibiotics ceftriaxone and benzathine penicillin G behave in the bodies of pregnant women. Researchers will measure drug levels in the blood during different trimesters and check for side effects. Up to 78 pregnant women and about 22 of their infants …

This study looks at how quickly the stomach empties in women during early labor when they drink either water or a carbohydrate sports drink. Researchers want to see if the type of drink or having an epidural changes stomach emptying time. About 108 pregnant women at 36 weeks or m…

This study aims to create a special scoring system for pregnant and recently postpartum women in the intensive care unit (ICU) to better predict their risk of dying. Researchers will collect routine medical data from 130 participants to see if a pregnancy-adjusted score works bet…

This study looks at whether sipping water or a carbohydrate-rich drink before a planned C-section is safer and helps women recover better. About 190 women will be randomly assigned to one of the two drinks. Researchers will use ultrasound to check stomach contents and ask women a…