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New MRI technique peers into the placenta to uncover Obesity's hidden impact on pregnancy

NCT ID NCT06314009

Knowledge-focused Sponsor: Endeavor Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will use a special type of MRI (fMRI) to measure blood flow and oxygen levels in the placenta during the second and third trimesters of pregnancy. Researchers want to see if these measurements differ between women who were obese before pregnancy and those with a normal weight. The goal is to better understand how obesity may affect the placenta and pregnancy outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better understand how obesity affects the placenta during pregnancy, potentially leading to earlier detection of complications.
What could go wrong
This is a small, early-stage observational study (30 people) that only measures differences—it does not test a treatment. Results may not apply to all pregnancies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Pregnant people at 20-24 weeks gestation. 15 obese (OB) women and 15 normal weight (NW) will be recruited to participate in the study. OB is defined as pre-pregnancy body mass index greater than or equal to 30 kg/m2, and NW is defined as pre-pregnancy body mass index between 18.5-24.9 kg/m2 without comorbidities.

Ages

18 to 60 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Singleton pregnancy, less than 24 weeks gestation * Pre-pregnancy BMI between 18.5 - 24.9kg/m2 or ≥30kg/m2 Exclusion Criteria: * Asthma on controller medication * Autoimmune Conditions * Chronic Hypertension * Claustrophobia * Congenital Anomaly * Pregestational Diabetes * History of Bariatric Surgery * HIV * Ineligible for MRI (incompatible implanted medical device) * Multifetal Gestation * Smoking during pregnancy

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Conditions

The condition(s) this trial relates to.

Body Weight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pregnancy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Endeavor Health

    RECRUITING

    Evanston, Illinois, 60201, United States

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