PREGNANCY

This study tests the MVA-BN mpox vaccine in 359 pregnant and postpartum women in the Democratic Republic of the Congo. Some women get the vaccine during pregnancy, others right after birth, and a small group gets it as an emergency shot after mpox exposure. Researchers will check…

This study tests whether having more postpartum visits with an obstetric provider or nurse helps mothers with high blood pressure or diabetes manage their health during the first year after giving birth. 100 mothers with Medicaid insurance are taking part. The goal is to see if t…

This study tests whether group prenatal care, where women with diabetes meet together with a healthcare provider, works better than standard one-on-one visits. Researchers will track blood sugar levels and weight after delivery in 117 pregnant women with type 2 or gestational dia…

This study looks at whether a short course of TB prevention drugs (isoniazid and rifapentine) is safe for pregnant women with HIV. About 252 pregnant women will receive either a daily regimen for one month or a weekly regimen for three months. Researchers will also check how thes…

This study looks at whether taking omega-3 fatty acid supplements can help lower very high triglyceride levels in pregnant women. High triglycerides during pregnancy can increase the chance of having a large baby. The study involves 40 pregnant women with elevated triglycerides a…

This study tests whether combining text message support for pregnant smokers with special training for their OB doctors helps more women quit smoking. About 840 pregnant women who smoke will take part. Both groups get quit-smoking texts, and some doctors get extra counseling trai…

This study looks at whether attending group nutrition and cooking classes during pregnancy helps women gain weight within recommended ranges. About 216 women with uncomplicated pregnancies will either attend these classes or receive standard care with a brochure. Researchers will…

This study looks at whether delivering healthy meals to the homes of low-income Black pregnant women can improve their diet, help them gain the right amount of weight during pregnancy, and support better blood pressure. About 17 women with overweight or obesity are receiving meal…

This study tests a team-based care model for pregnant and postpartum women with opioid use disorder in low-resource clinics. About 1,350 participants will receive coordinated support to start and stay on medication, reduce overdose risk, and improve well-child visits. The goal is…

This study tests a mobile health program (i-PregMom app) to help pregnant women control their blood sugar and weight gain. About 160 first-time mothers will use the app from early pregnancy (10-14 weeks) to mid-pregnancy (24-28 weeks). The goal is to see if the app improves healt…

This study tests whether giving vitamin B2 (riboflavin) and a form of folate (5-MTHF) to pregnant women with a specific gene variant can prevent high blood pressure. About 2250 women in their first trimester are being recruited. Those with the gene variant receive the vitamins or…

This study tests whether screening pregnant women for malaria in the first trimester using a highly sensitive rapid test, followed by treatment if positive, can prevent serious pregnancy problems. Over 2,100 women in malaria-prone areas will be compared to those receiving standar…

This pilot study is testing a lifestyle physical activity program to help pregnant women cut down on cannabis use. The study includes 50 pregnant women aged 18 and older who used cannabis at least once a week before pregnancy and want to stop. Participants will be guided to incre…

This study tests whether a structured exercise program during the second and third trimesters of pregnancy can improve the mother's fitness, blood vessel health, and weight gain, as well as the baby's health at birth. Sixty-four first-time pregnant women will participate. The goa…

This study tests whether a mindfulness-based childbirth and parenting class can lower anxiety in pregnant women. Sixty women with elevated worry will be randomly assigned to either the mindfulness class or a standard childbirth education class. Researchers will track changes in a…

This pilot study tests a 10-week mindful eating self-help program for pregnant women who binge eat. Participants use a book and a smartphone app to learn mindful eating skills. The study aims to see if the program is feasible, acceptable, and helpful for reducing binge eating and…

This study looks at whether eating three dates each morning can help reduce vomiting and improve hemoglobin levels in pregnant women experiencing morning sickness. Forty pregnant women will be randomly assigned to eat dates, take standard anti-nausea medication, or follow dietary…

This pilot study tests whether giving calcium carbonate to pregnant women during labor induction can shorten the time needed and reduce the need for C-sections. Researchers will compare 250 women who receive calcium with a historical control group. The goal is to see if this simp…

This study tests whether adding a substance called cpFT to the liquid used to grow eggs and embryos can increase the number of live births in women under 37 who are having a type of IVF called ICSI. About 366 couples took part. The goal is to see if this simple change can improve…

This study tests whether listening to educational podcasts can reduce intense fear of childbirth in couples. About 50 pregnant women and their partners will be randomly assigned to receive podcast training or standard care. The goal is to lower anxiety, improve emotional well-bei…

This study looks at whether teaching ThetaHealing meditation to first-time pregnant women can help reduce their pain and fear during labor. Forty healthy women in their first pregnancy will learn the meditation method before birth and use it during labor. Researchers will also us…

This study tests a device called Emagina that uses a small balloon to train the pelvic floor muscles during pregnancy. The goal is to see if it makes the perineum more flexible and reduces tears or the need for stitches during childbirth. About 88 first-time mothers will either u…

This study looks at whether progressive muscle relaxation and finger grip exercises can lower stress, anxiety, and fatigue while improving sleep in pregnant women with preeclampsia. About 90 women will be split into three groups: one doing relaxation exercises, one doing finger g…

This study tests whether using a virtual reality (VR) relaxation program can reduce nausea and vomiting, improve sleep quality, and increase comfort in pregnant women. About 90 women in early pregnancy (6-14 weeks) will either use VR relaxation or receive standard care. The goal …

This study follows 9,000 pregnant women in Zambia from early pregnancy through one year after birth. Researchers collect medical details and biological samples to uncover why preterm birth occurs, with the goal of finding new prevention strategies. It is an observational study, s…

This study looks at whether taking DHA (an omega-3 fatty acid) supplements during pregnancy can improve maternal health and infant development. Researchers are giving 168 low-income African American women either DHA or a placebo daily for 24 weeks. They will measure stress levels…

This study adapts an existing stigma-reduction program specifically for pregnant and postpartum women living with HIV in Ghana. Researchers will interview 30 women and 20 providers to understand their experiences, then work with stakeholders to tailor the program. Finally, 90 pre…

This study is creating a biobank at San Raffaele Hospital in Milan to collect blood samples and health data from 3,000 people. The goal is to support research into gynecological disorders, male and female infertility, and pregnancy-related conditions. No treatments are being test…

This study tested a 30-minute online training for doctors and nurses to help them counsel pregnant patients about workplace rights and accommodations. The trial was withdrawn before enrolling any participants, so no results are available. The goal was to see if the training could…

This study uses insurance claims data to see if taking the constipation drug prucalopride during pregnancy is linked to birth defects or other problems for mothers and babies. Researchers will compare pregnant women who took prucalopride, those who took other constipation medicin…

This study tests whether using virtual reality (VR) during a C-section can lower the chances of postpartum depression and anxiety. Researchers will compare 98 pregnant women who use VR during surgery to those who don't, measuring mood and brain chemicals linked to depression. The…

This study gathers expert doctors to agree on safe skin care practices during pregnancy. It focuses on which ingredients and treatments are safe for both mother and baby, like vitamin C and mineral sunscreen, and which to avoid, like retinoids. The goal is to provide clear, trust…

This study is exploring what happens when women have better financial access to birth control. Researchers are tracking about 5,000 women in Michigan to see how it affects their use of contraception, pregnancy rates, education, jobs, finances, and overall well-being. The goal is …

This study follows pregnant women who took Wegovy for obesity or overweight to see if it affects the baby's health. Researchers compare these women to similar pregnant women who did not take Wegovy. The goal is to check for birth defects and other health issues in infants during …

This study uses donated placentas from healthy pregnancies to measure how much sugammadex, a drug used to reverse anesthesia, passes from mother to baby. Researchers will test drug levels in both the maternal and fetal sides of the placenta in a lab model. The goal is to provide …

This study looks at sleep health in 50 low-income pregnant women. Researchers will use a home sleep test and a wrist activity monitor to measure sleep. They want to see how sleep relates to heart health and social factors. The goal is to create better sleep screening and treatmen…

This study aims to understand how drugs like cocaine, alcohol, marijuana, and cigarettes taken during pregnancy affect the way mothers and babies bond. Researchers will look at the baby's brain and behavior shortly after birth. The study involves 150 mothers and their newborns.

This study tests a special education program for first-time mothers that combines hypnosis techniques with breastfeeding information. The goal is to see if it helps mothers feel more confident and motivated to breastfeed. About 80 healthy pregnant women will take part, and resear…

This study looks at how a mother's stress and mental health may affect her body's ability to handle sugar during pregnancy, which is linked to gestational diabetes. Researchers will study 150 pregnant women to find patterns that could help identify those at risk earlier. The goal…

This study looks at health records of about 1,100 women who took Wegovy during pregnancy and compares them to those who did not. The goal is to see if the drug increases risks for birth defects or other problems in babies. Researchers will use insurance claims data to track outco…

This study looks at how to help VA medical centers offer virtual programs that prevent heart disease, diabetes, and depression in women Veterans. Researchers are testing two different support strategies at 20 VA sites to see which works better. The study does not involve patients…

This study aims to understand how the body's response to insulin changes during pregnancy in people with type 1 diabetes. Researchers will analyze data from continuous glucose monitors and insulin pumps used by 100 participants from before pregnancy to six months after birth. The…

This study looks at whether showing a short video to pregnant women at least 24 hours before a planned C-section helps them better understand the risks and benefits of anesthesia. Researchers will compare how well these women make informed decisions about their care versus those …

This study was designed to see if a special MRI technique could measure blood flow in the placenta during pregnancy. The goal was to compare placentas in pregnancies where the baby is growing poorly (IUGR) with healthy pregnancies. However, the study was withdrawn before any part…

This study looks at whether a simple urine pregnancy test taken 2 weeks after a medication abortion can reliably show the abortion is complete, instead of waiting the usual 4 weeks. About 400 people with very early pregnancies (up to 42 days) will take weekly tests and answer sym…

This study was designed to see if a device called ClearSight™ can accurately measure blood flow changes in pregnant women at term. Researchers planned to compare it with a standard ultrasound method during a leg-raising test. The goal was to help doctors give fluids more safely d…

This study aims to create clear, expert-backed recommendations for using vitamins, minerals, and other supplements during pregnancy. Currently, there is a lot of variation in how doctors prescribe these products. The study will involve 15 specialists who will answer questions in …

This study looks at whether a brief home visitation program for pregnant and new mothers can help them connect with community resources, feel more confident about their health, and lower their stress. Half of the 450 participants will receive free home visits from a non-nurse vis…