Personalized vitamin plan may shield pregnant women from high blood pressure
NCT ID NCT04723836
First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 33 times
Summary
This study tests whether giving vitamin B2 (riboflavin) and a form of folate (5-MTHF) to pregnant women with a specific gene variant can prevent high blood pressure. About 2250 women in their first trimester are being recruited. Those with the gene variant receive the vitamins or a placebo from week 16 until delivery. The goal is to find a simple, non-drug way to manage blood pressure in pregnancy.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Locations
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Letterkenny University Hospital
Letterkenny, Ireland
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Northern Health and Social Care Trust
Coleraine, N.Ireland, BT52 1HS, United Kingdom
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Western Health and Social Care Trust
Londonderry, N.Ireland, BT47 6SB, United Kingdom
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Riboflavin (Vitamin B2) and 5-methyltetrahydrofolate (a form of folate)
What this could lead to
If it works, this could lead to a simple, non-drug way to prevent high blood pressure during pregnancy for women with a specific gene variant.
What could go wrong
This is an early-stage trial focused on a specific gene variant, so results may not apply to all pregnant women. The supplements may not lower blood pressure as hoped.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.