PREGNANCY

This study will enroll about 10,000 pregnant women in Lombok, Indonesia, to see if digital tools like WhatsApp reminders and a call center can help them stick to taking daily multiple micronutrient supplements. It will also compare two types of packaging—bottles vs. blister packs…

This study looks at whether structured nutrition counseling helps pregnant women with gestational diabetes improve their diet quality and reduce harmful substances called advanced glycation end products. About 48 first-time pregnant women aged 18-35 will be assigned to either cou…

This study will test the MiniMed 780G insulin pump with continuous glucose monitoring in 20 pregnant women with type 2 diabetes. Participants join before 16 weeks of pregnancy and use the pump until delivery. The goal is to see if the pump helps keep blood sugar in a safe range (…

This study tests whether eating a balanced meal made from local foods once a day during pregnancy can help women in rural Pakistan handle heat stress better and have healthier babies. About 292 women will either eat this meal daily or continue their usual diet. Researchers will m…

This study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during routine prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not part of standard pregnancy care. The study will compare …

This study looks at whether giving extra progesterone injections for 6 weeks after a positive pregnancy test can improve live birth rates in women aged 18-37 who have low progesterone levels after a fresh embryo transfer. Half of the 214 participants will receive the extra proges…

This study looks at two different approaches to help pregnant people with gum disease get better dental care. Participants will receive free dental check-ups, cleanings, and supplies. The goal is to see which method reduces gum inflammation and improves oral health habits, and wh…

This study looks at whether a noninvasive finger monitor can predict how pregnant women, including those with severe preeclampsia, respond to fluids. Researchers will compare the finger device to standard heart ultrasound in 88 women. The goal is to find a simpler way to guide fl…

This study will check if a simple finger prick blood test gives the same pregnancy hormone (beta-hCG) results as a standard blood draw from a vein. Researchers will compare both methods in 40 pregnant women. If finger stick blood works just as well, it could make pregnancy testin…

This study checks if a new home pregnancy test (Clara Multi-Level) gives the same results whether used by a person at home or a trained professional. About 180 women will take the test at the study center and answer questions about using it. The goal is to make sure the test is e…

This study tests a personalized support program called PTBCARE+ for pregnant individuals at high risk of delivering early. The program includes a stress reduction toolkit, a website/app, care coordination, and optional massage. Researchers will compare stress levels and birth out…

This study will test whether giving women healthy lifestyle education before they get pregnant or in early pregnancy can improve their heart health and lower the chance of problems like gestational diabetes and preeclampsia. Two hundred women at risk for preeclampsia will be rand…

This study tests different combinations of an online program called CARRII, designed to help Native American women reduce their risk of alcohol-exposed pregnancy. Over 500 participants will be randomly assigned to one of eight versions of the program for three months. The goal is…

This study compares a single daily pill (Dual Prevention Pill) against taking two separate pills to prevent HIV and pregnancy in 300 women without HIV. Participants will try both approaches to see which leads to better daily use. The goal is to make prevention simpler and more ef…

This study tests a counseling program called Healthy Families-PrEP that helps women in rural Uganda use HIV prevention medicine (PrEP) when trying to get pregnant, during pregnancy, and after giving birth. About 660 women who are HIV-negative but at risk will take part. The goal …

This study tests whether a mobile app with short weekly exercises can help first-time parents manage emotions and reduce depression during pregnancy. About 572 expectant mothers and fathers in Singapore will use the app or receive standard care. Participants will also wear a Fitb…

This study compares using an injection port versus standard single-use needles for giving insulin to pregnant women with diabetes. The port is placed on the skin and changed every few days, allowing insulin to be delivered without repeated needle sticks. Researchers want to see i…

This study tests if using special absorbable staples to close the skin after a C-section works better than the usual method. About 237 women having a C-section will take part. The goal is to see if the staples make the surgery faster and lead to a nicer-looking scar.

This study will test a 4-week mindfulness-based stress reduction program for first-time pregnant women. The goal is to see if it can lower anxiety about the baby's health and improve overall psychological well-being. One hundred women will participate, and the program includes we…

This study is testing a virtual reality (VR) program designed to help pregnant women feel more prepared for childbirth and improve their mental wellbeing. The researchers will enroll 68 first-time mothers who are at least 20 weeks pregnant. Participants will use the VR platform o…

This pilot study will test whether it is safe and practical for pregnant women with type 1 or type 2 diabetes to continue using their insulin pump during labor, instead of switching to IV insulin. About 30 women who already use an insulin pump will be allowed to keep using it dur…

This study looks at whether eating milk chocolate during labor can shorten the pushing stage (second stage) for healthy pregnant women. 180 women with a single baby at full term will be randomly assigned to eat chocolate or receive no food. The goal is to see if the extra energy …

This study aims to see if using a standard method for cervical ripening (softening the cervix before labor) increases the chance of a vaginal delivery. About 1,158 pregnant women scheduled for labor induction will be randomly assigned to one of two standard approaches. The goal i…

This study will test whether virtual doula services improve birth outcomes and satisfaction for first-time mothers living in rural areas. About 614 pregnant women in their second or early third trimester will be recruited nationwide. Participants will receive doula support via vi…

This study looks at whether using a weighted blanket can reduce nighttime leg cramps, improve sleep quality, and lower anxiety and stress in pregnant women. Fifty women in their third trimester will use the blanket for 14 days and compare results to a 14-day period without it. Th…

This study tests whether using a breast pump for nipple stimulation can safely start labor in pregnant women. The gentle suction may trigger the body's own oxytocin to encourage contractions. Researchers will measure total labor time and compare it to standard methods. The goal i…

This study tests a mindfulness-based psychoeducation program for pregnant women who are very afraid of childbirth. The program includes group sessions twice a week for 4 weeks, teaching relaxation and coping skills. Researchers will measure fear levels, self-perception, and spiri…

This study compares two ways to manage pain after a planned C-section: a small dose of morphine given with the spinal anesthesia, versus a nerve block (TAP block) using numbing medicine. One hundred women will be randomly assigned to one of the two groups. The goal is to see whic…

This study tests an online program called STORK that helps couples expecting their first baby manage changes in their sexual relationship. About 268 couples will take part, starting during pregnancy and continuing until 12 months after birth. The program provides information and …

This study tests whether a 10% lidocaine spray can reduce the pain of inserting an IV needle in women scheduled for a C-section. About 150 participants will receive either the spray or a placebo before IV insertion and rate their pain on a 0–10 scale. The goal is to see if the sp…

This study tests whether a weekly exercise program, plus extra pelvic floor therapy if needed, can reduce pelvic girdle pain in pregnant women. About 40 women with pelvic pain will be randomly assigned to either the exercise program or standard care. The goal is to see if this ap…

This study tests a structured education program for first-time pregnant women to reduce fear of childbirth and stress, and to strengthen their belief in normal birth. About 72 women in their third trimester will either receive the program or standard prenatal care. The goal is to…

This study works with patients and healthcare professionals to create educational resources about fertility and pregnancy for people with Primary Ciliary Dyskinesia (PCD). The goal is to develop a patient-friendly guide and a toolkit for doctors. The study will involve 30 partici…

This study will follow 120 women with twin pregnancies and their 240 children to understand how environmental exposures, lifestyle, and diet during pregnancy and early life affect health. Researchers will collect biological samples and track health outcomes from birth to one year…

This pilot study will test whether a single 60-minute group session about safe exercise during pregnancy can improve women's knowledge, confidence, and physical activity levels. Thirty pregnant women with low-risk pregnancies will be randomly assigned to receive either standard p…

This study follows 1,000 pregnant women and their partners from early pregnancy to about two months after birth. Participants fill out short questionnaires at key timepoints to track how their health information needs change. Some may also share data from their smartphones or wea…

This study follows 376 pregnant women from late pregnancy to 12 weeks after birth. Researchers measure hip, pelvic, and abdominal muscle function to see if these factors are linked to how a baby is delivered (vaginal or cesarean) and whether women develop pelvic floor problems li…

This study will test whether regularly screening pregnant women for certain genital infections (even if they have no symptoms) can reduce problems like preterm birth and low birth weight. About 250 pregnant women will be split into two groups: one gets the extra screening and tre…

This study tests a 30-minute online training for obstetric providers to help them counsel pregnant patients about workplace rights and accommodations. Researchers will compare how often work-related counseling is documented and whether patients experience less wage loss or better…

This study tests whether listening to binaural beats (a type of sound pattern) can lower the amount of midazolam, a sedative, needed during cesarean sections done under spinal anesthesia. Researchers will compare two groups of pregnant women: one listening to binaural beats and o…

This study will measure a substance called kynurenine in the blood of 204 pregnant women, some with chronic kidney disease and some without. The goal is to see if kynurenine levels are linked to preeclampsia, a serious condition that can harm both mother and baby. Researchers hop…

This study looks at how physical activity changes during pregnancy in women with type 1 or type 2 diabetes, and how it relates to blood sugar control and mental health. About 175 pregnant women will wear activity monitors and share glucose data. The goal is to learn what support …

This study tests whether a short video of Black women sharing their labor pain experiences can increase empathy in doctors and nurses. About 120 providers and their Black postpartum patients will take part. The goal is to see if this simple tool improves trust and understanding i…

This study tests whether AI-assisted ultrasound devices can help frontline health workers in rural Ethiopia detect pregnancy problems early. About 1,059 pregnant women will be split into three groups: two using different AI ultrasound tools and one receiving standard care without…

This study will test better ways to screen for tuberculosis (TB) in pregnant and postpartum women in Guinea-Bissau. Researchers will use a symptom checklist, stool tests, and AI-powered chest X-rays to find more TB cases. The goal is to improve health for mothers and babies and g…

This study looks at how doctors trust artificial intelligence (AI) when estimating a baby's weight during pregnancy. About 308 clinicians will review ultrasound cases and compare AI estimates with traditional methods. Some doctors will see extra info about the AI's accuracy, whil…

This study looks at whether teaching first-time mothers how to do perineal massage during pregnancy can help them feel more in control, confident about a normal birth, and less afraid of childbirth. About 152 pregnant women in Turkey will either get this special education plus re…

This study will test whether a mobile app called MI MOM can improve pregnancy and postpartum health for 500 pregnant women on Medicaid. One group uses the app and gets text messages with health tips, videos, and optional support from a community health worker. The other group rec…

This study tests a simple tool—short information cards on a mobile phone—to help pregnant people feel more confident when deciding about prenatal genetic screening. About 1,400 participants will use the cards before their first doctor visit, or receive usual care. Researchers wil…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant patients before they receive anesthesia during delivery. About 250 first-time mothers will take part, and researchers will compare how complete and accurate the i…

This study looks at how cystic fibrosis medications (CFTR modulators) change in the body during pregnancy and after childbirth in 30 women. Researchers will measure drug levels in blood, breast milk, and umbilical cord blood. The goal is to understand how these drugs work in preg…

This study tests a smartphone app called Womb Watch that uses the phone's microphone to listen to fetal movements, like kicks and hiccups. Researchers will enroll 60 pregnant women (both low- and high-risk) to see if the app is easy to use and accurate. The goal is to provide a s…

This study looks at how daily routines like sleep, activity, and meal timing in early pregnancy relate to blood sugar patterns and the risk of gestational diabetes. About 140 pregnant women without diabetes will wear monitors and use a food app to track their habits. The goal is …

This study will collect ultrasound images from 50 pregnant people between 18 and 28 weeks of pregnancy. The goal is to use these images to train artificial intelligence (AI) to automatically measure key parts of the baby, like head size and leg length. The results will help get t…

This study looks at how often pregnant women who have their water break early carry antibiotic-resistant bacteria. Researchers will collect samples from 250 women across French hospitals to track these bacteria and identify risk factors. The goal is to help doctors choose better …

This study looks at how body image dissatisfaction, eating behaviors, and daily stress relate to blood sugar levels in pregnant women. Researchers will monitor 50 women between 14 and 28 weeks of pregnancy using a continuous glucose monitor and daily surveys over 10 days. The goa…

This study tests whether special educational sessions can help first-time mothers breastfeed exclusively. 160 pregnant women will either attend four weekly classes on breastfeeding skills and confidence or receive standard care. Researchers will check how many are still exclusive…

This observational study follows 111 women with multiple sclerosis who received rituximab (or similar CD-20 antibodies) before or during pregnancy, and their infants. Researchers will measure the baby's B-cell levels, infection rates, and vaccine responses during the first year o…