University Of British Columbia

This study is testing whether a 6-month program combining exercise, mindfulness, and healthy eating can improve brain health and potentially slow the progression of Parkinson's disease. It will involve 60 people aged 40-85 who have been diagnosed with Parkinson's or a related sle…

This study aims to find out if careful monitoring works just as well as bracing for babies under 3 months old with mild hip dysplasia. Researchers will compare two groups: one receives the standard brace treatment, and the other is simply observed with regular check-ups. The goal…

This study is testing a new gel form of chemotherapy called ST-02 for treating low-grade tumors in the upper urinary tract (kidney and ureter). Participants will receive the gel directly into the kidney area once a week for six weeks to see if it can destroy the cancer without ne…

This study is testing if more frequent monitoring of vital signs after major surgery helps patients recover better. It will compare patients who receive continuous monitoring in the hospital and at home for a few days to those who get standard, less frequent checks. The main goal…

This project aims to reduce child malnutrition in Pakistan by teaching families better feeding and care practices using local resources. It focuses on mothers of moderately malnourished children aged 7-15 months. The core program involves a 28-day cycle of group learning sessions…

This study compares two common surgeries for stress urinary incontinence in women aged 60 and older. Researchers will randomly assign participants to receive either a synthetic mesh sling or a sling made from the patient's own tissue. The main goals are to see which surgery has a…

This small, early-stage study is testing whether therapy sessions guided by the psychedelic compound psilocybin can help people with chronic pain safely reduce or stop their opioid pain medication. The study will involve 10 adults who have previously struggled to taper off opioid…

This study is testing if hiring peer support workers—people with personal experience using drugs—in a busy emergency room can help patients who use substances feel safer and more comfortable. The goal is to see if this support encourages patients to stay and complete their medica…

This study aims to reduce unnecessary blood tests for adult patients in 16 BC hospitals. Researchers will provide doctors with education, decision-support tools, and data reports to help them order only the tests patients truly need. They will measure if this approach safely redu…

This study is testing whether a special support program helps young adults with type 1 diabetes manage their blood sugar better during the challenging transition from pediatric to adult care. Researchers will compare the new program, which provides tailored coaching to build inde…

This study is testing whether following a Mediterranean-style diet for 18 months can help manage Parkinson's disease symptoms by influencing gut health. Researchers will compare this special diet to standard eating habits in 40 people with Parkinson's, tracking symptoms, gut bact…

This study is comparing two different physiotherapy counseling methods to help older adults with early frailty become more physically active. It will involve 20 physiotherapists and their patients across Canada. The goal is to see if a new approach focused on balancing activity, …

This study is testing whether a 6-month weight training program can improve memory and thinking skills in perimenopausal women who are noticing cognitive difficulties. Researchers will compare weight training to a balance and stretching program in 50 inactive women aged 40-55. Th…

This study is testing whether women with Lynch syndrome can use simple home vaginal swabs to detect early signs of uterine cancer. Researchers want to see if these self-collected samples can find DNA changes that might indicate cancer risk. The study also checks if participants f…

This study is testing whether eating more fatty fish, fruits, and vegetables can help protect healthy lungs from the harmful effects of woodsmoke. Researchers will have 48 healthy adults breathe woodsmoke while following either this special diet or their regular diet. They will m…

This study is testing whether two doses of the HPV vaccine work as well as the standard three doses for women living with HIV. The goal is to prevent HPV infection and the cervical cancer it can cause. Researchers will compare the immune response in women who get two shots versus…

This pilot study is testing whether a non-invasive electrical stimulation applied to the skin over the spine can help improve automatic body functions that are often disrupted after a spinal cord injury. Researchers are recruiting 30 adults with chronic spinal cord injuries to se…

This study is testing whether a 6-month exercise program can help improve sleep quality for adults who have had a stroke at least a year ago and currently have poor sleep. Researchers will compare a group doing twice-weekly exercise with a group doing social and cognitive activit…

This study is testing whether a non-invasive electrical patch placed on the back can help improve bladder, bowel, and sexual function for people with spinal cord injuries. It will involve 60 participants, including Ukrainian war veterans, who will receive either the real stimulat…

This study is testing an 8-week online program called STEP, designed to help couples who are distressed because they have different levels of sexual desire. Researchers are comparing two versions: one with live therapist support via video calls, and one that is self-guided with w…

This study is testing whether a daily probiotic supplement can help reduce depression in people who have Parkinson's disease. About 60 participants with mild to moderate Parkinson's and depression will take either the probiotic or a placebo pill for 12 weeks. Researchers will mea…

This study is testing whether a 6-month health coaching program can help older adults with limited mobility become more physically active and improve their movement and function. It will compare the coaching program to a general health education program. Researchers will measure …

This study is testing a free, 3-month virtual coaching program designed for people waiting for hip or knee replacement surgery. The program aims to help participants stay active, manage pain, and reduce feelings of loneliness while they wait. Researchers want to see if the progra…

This study is testing whether combining leg nerve stimulation with standing therapy can improve bladder control and quality of life for people with chronic spinal cord injuries. Researchers will work with 12 participants to see if this 12-week program is practical and helps reduc…

This study is testing whether virtual reality (VR) exposure therapy can help people with vaginismus, a condition where fear causes involuntary pelvic muscle tightening, making penetration painful or impossible. Twenty participants will use VR to gradually face their fears in a sa…

This study is testing an online program designed to help gynecologic cancer survivors manage sexual health concerns that often arise after treatment. Researchers want to see if this digital approach can effectively reduce distress and improve sexual function for 60 participants. …

This pilot study aims to find out if giving protein in large, spaced-out doses (bolus) is better than a slow, steady drip (continuous) at helping critically ill children ages 1-11 maintain their weight and muscle mass. Researchers will compare the two methods by measuring the chi…

This study aims to confirm that brain function does not return in organ donors after they have been declared dead. Researchers will monitor brain activity in 30 organ donors during organ preservation procedures. The goal is to ensure current organ donation practices are safe and …

This study aims to understand how listening to personally chosen music might help reduce apathy—a common lack of motivation and emotion—in people with Parkinson's disease. Researchers will enroll 50 participants to use an 8-week music listening program while measuring changes in …

This study aims to understand if a common asthma medication (salbutamol) can improve exercise performance in non-asthmatic endurance athletes. Researchers are recruiting 64 healthy male and female runners and cyclists to test if the drug helps a specific group who experience brea…

This study aims to discover if patterns in a person's gut bacteria can predict how well Crohn's disease treatments will work. Researchers will collect stool, blood, and tissue samples from 100 adults with Crohn's disease in British Columbia, comparing them to people without the c…

This study aims to track the long-term safety and performance of orthopedic implants in children. It will follow 4000 young patients who receive devices for conditions like fractures, limb deformities, or hip problems. The goal is to collect real-world data on how well the implan…

This study aims to understand how histamine, a chemical best known for causing allergy symptoms, affects blood flow to the lungs after exercise. Researchers will recruit 20 healthy young adults to see if blocking histamine changes how the heart and lungs handle increased blood fl…

This study aims to understand and improve how emergency rooms across Canada care for people who have overdosed on opioids like fentanyl. Researchers will create a national registry by tracking the treatment and outcomes of 7,200 patients who come to the ER with an opioid overdose…

This study aims to understand if Cambodia's health system is ready to provide a new, more comprehensive prenatal vitamin supplement to pregnant women nationwide. Researchers will interview healthcare workers, pregnant women, and government officials, and check supply chains in on…