Gut feeling: could a probiotic lift mood in Parkinson's?

NCT ID NCT05568498

Recruiting now Symptom relief Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily probiotic supplement can help treat depression in people with Parkinson's disease. Sixty adults with mild to moderate Parkinson's and depression will take either the probiotic or a placebo for 12 weeks. Researchers will measure changes in mood and fatigue using standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Probiotic (Ecologic® BARRIER 849)
What this could lead to: If it works, this could offer a simple, natural way to improve mood in people with Parkinson's disease.
What could go wrong: This is a small, early-phase trial. The probiotic may not work better than a placebo, and results may not apply to everyone with Parkinson's.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION PARKINSON DISEASE PARKINSON DISEASE (DISORDER)

Contacts and locations

Locations

Pacific Parkinson's Research Centre
RECRUITING

Vancouver, British Columbia, V6T2B5, Canada

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