At-Home swab could spot uterine cancer in lynch syndrome patients

NCT ID NCT07194551

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether people with Lynch syndrome can use a self-collected vaginal swab at home to detect early signs of uterine cancer. Researchers will enroll 30 participants who will collect samples and answer surveys. The main goal is to see if this approach is practical and acceptable, not yet to prove it works for cancer detection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Vaginal DNA swab, microbiome swab and pH test
What this could lead to
If successful, this could lead to a simple, at-home screening method for uterine cancer in people with Lynch syndrome, potentially catching cancer earlier.
What could go wrong
This is a small, early feasibility study with only 30 participants. It is not designed to prove the test detects cancer, only that people can and will use the kit.

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Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis endometrial cancer endometrium neoplasm Lynch syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • VGH Research Pavilion

    RECRUITING

    Vancouver, British Columbia, V5Z 1M9, Canada

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