University Of British Columbia

This study is testing whether a non-invasive brain stimulation technique called iTBS can help reduce depression symptoms in young women. It will involve 8 female participants aged 16-24 who are currently experiencing depression. The approach aims to stimulate brain activity in ar…

This study aims to find out if using absorbable stitches (which dissolve over time) is as good as permanent stitches for repairing small umbilical hernias. It will involve over 900 adults having elective surgery for hernias 2 cm or smaller. The main goal is to see if the hernia i…

This study is testing whether combining two types of safe, non-invasive stimulation—one to the brain and one to the spinal cord—can help improve arm and hand function in people with chronic spinal cord injuries in the neck. Twenty-four participants will receive either the combine…

This trial aims to find the best way to manage atrial fibrillation (AFib) in people who also have heart failure. It will compare two main approaches: using catheter-based procedures to restore normal heart rhythm versus using medications and devices to control the heart rate. The…

This study aims to see if giving dentists personalized reports about their opioid prescribing habits, along with educational materials, can help reduce unnecessary opioid use for dental pain. It will involve nearly 3,500 dentists in British Columbia, Canada. Researchers will comp…

This study is testing whether new ways to program deep brain stimulation (DBS) devices can help people with essential tremor who stopped responding to their standard DBS therapy. Five participants will try six different stimulation patterns in clinic, then use one at home for thr…

This study is testing if a specific diet plan can make a standard Crohn's disease medication work better for children. Researchers will compare children taking the drug alone to those who also follow the special diet. The goal is to help kids achieve better disease control, reduc…

This small, early-stage study is testing a new non-invasive neck device designed to help control breathing during sleep. Researchers will have 10 healthy participants wear the device at home to see if it safely reduces breathing pauses and is comfortable to use. The goal is to ga…

This study aims to find the best treatment approach for people with early oral cancer or pre-cancerous lesions that have a specific genetic change called p53 mutation. Researchers will compare different surgery strategies across three groups of patients to see which approach best…

This study is testing a new type of ultrasound scan to see if it can accurately detect and measure the severity of fatty liver disease. Researchers will compare the new ultrasound method against current standard tests like MRI and a device called FibroScan in 145 volunteers, incl…

This study aims to see if a single, low dose of the medicine indomethacin, given soon after birth, can safely prevent severe brain bleeds in babies born extremely early (before 26 weeks). Researchers will compare it to a placebo (saltwater) in up to 500 babies across multiple cou…

This study is testing whether a 6-month online educational program called Brain Health PRO can help people at risk for dementia improve their lifestyle habits. Researchers will enroll 700 Canadian adults aged 50-80 who have risk factors like family history, high blood pressure, o…

This study aims to find out if teens with eczema prefer to apply moisturizer while still in the shower or bath, or after they have towel-dried. Researchers will compare both methods over two months to see which one feels better and if it makes a difference for skin hydration and …

This small pilot study is testing whether a device called Calmer can help support brain development in very premature babies. The device mimics a parent's touch, heartbeat sounds, and breathing motion to help reduce stress when parents cannot be present. Researchers will use brai…

This study aims to see if giving doctors and nurse practitioners personalized feedback about their antibiotic prescribing habits helps them reduce unnecessary prescriptions. Over 7,600 healthcare providers in British Columbia will be randomly assigned to receive this feedback ear…

This study aims to understand what sensations women experience during planned C-sections performed with spinal anesthesia. Researchers will ask 310 participants about their feelings at specific moments during surgery and follow up for six months to see how these experiences affec…

This study aims to understand how the bacteria in a pregnant woman's gut and her diet might influence inflammation in her baby's gut after birth. Researchers will follow 80 pregnant women, some with and some without Inflammatory Bowel Disease (IBD), and their babies for a year. T…

This study aims to determine how much phenylalanine, an essential protein building block, women need during different phases of their menstrual cycle. Current nutrition guidelines are based on male studies and may not be appropriate for women. Researchers will use a safe, non-inv…

This study aims to understand how the sex hormones estrogen and testosterone directly control blood flow to the brain. Researchers will temporarily block hormone production in 50 healthy young men and women, then give the hormones back, while measuring brain blood flow at rest an…

This study aims to learn if performing back exercises with your arm fully overhead versus at shoulder level leads to more muscle growth. Twenty young, healthy adults who already lift weights will train one arm with each method for 12 weeks. Researchers will use MRI scans and stre…

This study aims to understand how much leucine, an essential protein building block, healthy pregnant women need during early and late pregnancy. Researchers will measure how the body uses leucine by having 40 participants eat carefully prepared meals and provide breath, urine, a…