New gel could zap kidney cancer without surgery

NCT ID NCT06124976

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests a gel form of the chemotherapy drug gemcitabine, called ST-02, for people with low-grade cancer in the upper urinary tract. The gel is placed directly into the kidney through a small tube. The goal is to see if it can destroy tumors within three months and remain safe. About 70 adults with small, low-grade tumors will receive six weekly treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ST-02 (mucoadhesive gemcitabine suspension)

What this could lead to

If it works, this could offer a less invasive way to treat low-grade upper urinary tract cancer, potentially avoiding surgery.

What could go wrong

This is an early-phase trial with only 70 participants. The treatment may not fully eliminate tumors, and side effects from the chemotherapy gel are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

renal pelvis/ureter urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre of Applied Urology Research, Nova Scotia Health Authority

    RECRUITING

    Halifax, Nova Scotia, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Men's Health Clinic

    RECRUITING

    Winnipeg, Manitoba, R3P 2S8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UHN - Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Vancouver Prostate Centre

    RECRUITING

    Vancouver, British Columbia, Canada

    Contact

    Contact

    Contact

    Contact