METABOLIC SYNDROME

This study looked at whether drinking hydrogen-rich water every day for 12 weeks can improve body fat, waist size, and blood markers in adults with metabolic syndrome. 40 people took part, some getting the hydrogen water and others a placebo. The goal was to see if this simple dr…

This study looked at 192 women with PCOS to see which treatment works best for improving insulin resistance, weight, and menstrual cycles. Participants were randomly assigned to take metformin, inositol, follow a calorie-restricted diet, or combine all three for 12 weeks. The goa…

This study tested whether a milk ingredient called milk fat globule membrane (MFGM) can reduce harmful gut bacteria products in the blood of adults with metabolic syndrome. Thirty participants followed a controlled diet with either MFGM-enriched milk or regular milk for two weeks…

This study tested whether eating a fermented pea- and legume-based product could improve gut health and reduce inflammation in people with metabolic syndrome. 56 participants ate both the fermented and unfermented versions for three weeks each. Researchers measured markers of inf…

This study looked at whether omega-3 supplements from plants can improve blood vessel function in people with high blood pressure and metabolic syndrome. About 95 adults with treated hypertension and at least two signs of metabolic syndrome took part. Researchers measured how wel…

This pilot study tested whether metformin, a standard diabetes drug, can reduce blood vessel damage and inflammation in the brain for people living with HIV who also have metabolic syndrome. Thirty participants received metformin for 12 weeks, and researchers measured changes in …

This study looked at how eating strawberries affects heart health and metabolism in 48 overweight or obese adults with borderline high cholesterol. Participants ate strawberries and researchers measured changes in blood fats, blood sugar, and insulin. The goal was to see if straw…

This study looked at 781 adults with moderate to severe plaque psoriasis and metabolic syndrome (a cluster of conditions like high blood pressure and obesity). Participants either received the drug Secukinumab alone or combined with a lifestyle intervention (diet and exercise adv…

This study looked at whether taking a natural plant supplement called phytosterol can help people with nonalcoholic fatty liver disease (NAFLD). 27 adults took the supplement for 3 months. Researchers measured changes in liver enzymes, cholesterol, insulin, and inflammation. The …

This study looked at whether replacing typical dietary fats with canola oil for 12 weeks could improve cholesterol, blood vessel function, and other heart disease risk factors in 80 adults with metabolic syndrome. Participants were men and women aged 20-75 with high LDL cholester…

This study tested whether vericiguat, a drug that helps blood vessels relax, could improve heart artery function in 45 adults with metabolic syndrome (a cluster of conditions like high blood pressure, large waist, and abnormal cholesterol). Participants took either vericiguat or …

This study looked at whether eating only during a specific window each day (time-restricted eating) combined with short, intense exercise (high-intensity interval training) can improve health markers in people with metabolic syndrome. 200 overweight or obese adults with metabolic…

This study looked at whether a 16-week strength training program can help adults who had a bone marrow transplant as children. The goal was to see if exercise can reduce muscle loss, heart disease, and diabetes risks that often appear years after transplant. 28 survivors and heal…

This study tested whether a blend of digital tools (video sessions and a health app) plus standard in-person care works as well as in-person care alone for children and teens with obesity. About 100 families in Sweden took part. The goal was to see if the digital-physical approac…

This study tested whether a home exercise program using electrical stimulation for leg muscles, combined with a healthy diet, could improve body composition and metabolism in adults with spinal cord injury. Twenty-six participants were assigned to either exercise plus diet or die…

This study tested whether a structured, intensive lifestyle program could help overweight or obese adults with metabolic syndrome achieve remission. 68 participants followed a program aimed at 15% weight loss. The goal was to see if this approach could reduce the number of metabo…

This study tested whether providing medically tailored meals (MTMs) alone or combined with weekly group support sessions helps Black adults with high blood pressure, type 2 diabetes, or obesity. 75 participants received either meals only, meals plus group support, or delayed meal…

This study looked at whether combining different doses of exercise with the diabetes drug metformin can improve blood vessel function and insulin sensitivity in adults with metabolic syndrome. 91 participants aged 40-80 were assigned to exercise programs with or without metformin…

This study tested whether a program of exercise combined with a daily drink containing leucine and arginine (amino acids) could help obese adults with metabolic syndrome lose body fat. 79 participants followed the program for several weeks. The main goal was to see if total body …

This study tested whether taking moringa leaf powder (5.5 grams daily for 8 weeks) can improve key signs of metabolic syndrome, such as belly fat, high blood sugar, and unhealthy cholesterol levels. Thirty-six Mexican adults with metabolic syndrome took part. The goal was to see …

This study involved 60 men with metabolic syndrome who also had erectile dysfunction and early signs of heart stiffness. Researchers tested whether tadalafil (an ED drug), SGLT2 inhibitors (diabetes medications), or a combination of both could improve sexual function and heart re…

This study looked at whether green tea extract can improve gut health and lower inflammation in people with metabolic syndrome and in healthy adults. 46 participants took either green tea extract or a placebo for one month, then switched to the other for another month. The resear…

This study tested whether eplerenone, a drug that blocks a hormone called aldosterone, can improve blood flow to the heart and reduce scarring better than a standard blood pressure drug (chlorthalidone) in people with obesity and high blood pressure. About 79 adults took part. Th…

This study tested the SWW Method®, a 12-week diet and lifestyle program, in 85 women aged 35-75. The program included intermittent fasting, a protein-rich diet, and other healthy habits. Researchers measured changes in blood sugar, weight, and other metabolic markers compared to …

This study tested whether drinking herbal infusions of VitalPLANT and Helichrysum italicum for one week can improve weight and cholesterol in 30 overweight adults with metabolic syndrome. Participants drank either VitalPLANT alone or a mix of both herbs, with a washout period in …

This study looked at whether eating only during certain hours of the day (early or late) helps overweight adults with metabolic syndrome lose weight and belly fat. About 100 adults followed either an early or late time-restricted eating plan. Researchers measured changes in body …

This study tested a black seed extract (Nisatol) in 50 perimenopausal women with metabolic syndrome. Researchers measured changes in blood sugar, cholesterol, blood pressure, and menopausal symptoms over 4 months. The goal was to see if this natural supplement could improve these…

This study looked at 51 adults with chronic lower back pain from a herniated disk who did not get better with basic treatments. Researchers wanted to see if having metabolic syndrome (a cluster of conditions like high blood pressure and high blood sugar) changed how well a steroi…

This completed study looked at 332 adults with obesity to see if simple body measurements and blood tests could predict metabolic syndrome—a cluster of conditions that raise heart disease and diabetes risk. Researchers grouped participants by obesity severity and calculated vario…

This study looked at whether a genetic score based on amino acid metabolism genes can predict how people with metabolic syndrome respond to a dietary intervention. 115 Mexican adults with obesity and metabolic syndrome took part. Researchers measured changes in waist size, blood …

This study tested whether a ketone ester supplement, taken for 28 days, could change how the brain uses fuel and affect thinking skills. It included 99 adults aged 55 and older who had metabolic syndrome but no memory problems. Participants were randomly assigned to receive eithe…

This study looked at a program called COPE that helps Navajo people with diabetes and other chronic conditions. The program uses community health workers to support patients and connect them with doctors. Researchers compared people in the program to those not in it to see if it …

This study looked at how daily rhythms affect fat cell genes and insulin response in 28 women with severe obesity scheduled for bariatric surgery. Researchers measured changes in fat cell insulin sensitivity before and 12 weeks after surgery. The goal was to understand the body's…

This study looked at 470 adults aged 18-75 with type 2 diabetes and metabolic syndrome to identify their Traditional Chinese Medicine (TCM) patterns. Researchers used a standard questionnaire and four TCM diagnostic methods to classify participants. The goal was to better underst…

This study looked at two easy methods to measure deep belly fat in 110 adults with type 2 diabetes. Researchers compared a simple waist measurement to a device that uses a mild electrical current (bioelectric impedance). The goal was to see which method better relates to heart di…

This study followed 215 people newly diagnosed with HIV in Hong Kong to see how often they developed non-AIDS health problems like high blood pressure, diabetes, bone thinning, and kidney issues. Participants were on different anti-retroviral drug regimens, and researchers compar…

This study tested whether a blood protein called PTX3 can predict how much weight people lose and how their metabolism improves after gastric bypass surgery. Researchers followed 23 adults with obesity for 6 months after surgery. The goal was to see if PTX3 levels before surgery …

This study followed 1100 adults with shoulder pain for one year to see if metabolic syndrome (a cluster of conditions like high blood pressure, high blood sugar, and excess belly fat) makes pain last longer. Researchers measured disability and work status to identify risk factors…

This study looked at 90 children and teens aged 7-18 who take antipsychotic drugs. Researchers measured hormone levels, growth, and metabolic health to understand side effects. The goal was to find safe limits for a hormone called prolactin and see how it affects puberty and grow…

This study in Cameroon followed 406 adults with and without type 2 diabetes for one year to see if diabetes increases the risk of malaria and other parasitic infections. Researchers tested blood and stool samples at four time points. The goal was to understand how diabetes and re…

This study followed 42 adults with spinal cord injury for one year after leaving rehab. Researchers tracked what they ate, how active they were, and factors like mood and kitchen access to understand why weight gain happens. The goal is to use this information to design better he…

This small pilot study looked at whether adding mindful attention to a walking program helps people with metabolic syndrome stick with physical activity. 34 participants were assigned to walking only, mindfulness only, walking plus mindfulness, or no program. The goal was to see …

This study examined 549 older adults (65+) to see if metabolic syndrome is connected to vitamin D levels, even in those without vitamin D deficiency. Researchers used surveys and blood tests to gather data. The goal was to better understand these relationships, not to test a trea…

This study examines whether the body's ability to switch between burning sugar and fat (metabolic flexibility) is linked to changes in metabolic health over 16 years. Researchers will re-evaluate 18 healthy participants from a 2008 study to measure weight, blood sugar, cholestero…

This study looked at how well people with stable coronary artery disease handle fats (triglycerides) and sugar after a meal. Over 18 months, researchers tracked heart attacks, strokes, and deaths to see if a fat-tolerance test could identify those at higher risk. The goal was to …

This study looked at whether a 12-month lifestyle program could lower body fat and change certain gene markers in adults with metabolic syndrome and obesity. Twenty-six participants tracked their diet and activity using a mobile app, and had blood tests and body scans at the star…

This study looked at how drinking orange juice compared to a sugary drink affects risk factors for heart disease and type 2 diabetes. Fifty-six adults drank either orange juice or a sugar-sweetened beverage for four weeks. Researchers measured changes in cholesterol, blood sugar …

This study tested whether a personalized lifestyle program could help people with obesity and related conditions like prediabetes or high blood pressure improve their insulin resistance. Forty adults received either nutrition or exercise counseling first, and if they didn't impro…

This study looked at how excess belly fat relates to the buildup of fatty deposits in arteries, known as atherosclerosis, which can lead to heart attacks. Researchers used MRI and CT scans to measure fat and plaque in 357 healthy adults aged 35-65. The goal was to better understa…

This study looked at 320 people with HIV in Chile, some with metabolic syndrome, to understand how ongoing inflammation affects their health. Researchers used advanced tools like single-cell sequencing and flow cytometry to analyze immune and inflammatory patterns. The goal was t…

This study tested whether people with major depression who eat a lot of ultra-processed foods could cut back on them. Twenty adults tried a personalized diet change for a short time. The goal was to see if it was possible and acceptable, not to measure health effects. Results wil…