METABOLIC SYNDROME

This study looks at whether a daily supplement containing inositols and alpha-lactalbumin can help people with metabolic syndrome who are at risk for heart scarring. About 30 adults will take the supplement to see if it improves blood sugar, blood fats, and blood pressure. The go…

This study looks at whether a weight loss program called "Paso a Paso" is practical for Mexican and Central American adults with fatty liver disease and overweight. Researchers will track attendance, weight loss, liver health, and diet changes in 50 participants. The goal is to s…

This study tests whether spermidine, a natural substance found in foods like wheat germ and soy, can improve heart and muscle health in people aged 65 and older with coronary artery disease. About 180 participants will receive either spermidine or a placebo for a period, and rese…

This study tests whether a 6-week, twice-weekly exercise program can improve physical and mental health in 100 adults with severe mental illness. Participants are randomly assigned to either usual care or usual care plus the exercise program. The goal is to reduce metabolic syndr…

This study tests a health behavior change program for 160 adults with both metabolic syndrome and chronic kidney disease. The program aims to reduce waist size and improve kidney function through better diet and physical activity. Participants are followed for one month after the…

This study looks at whether switching to a plant-based diet can improve heart health and reduce inflammation in people who have had a kidney transplant. About 25 adults who are at least 3 months post-transplant will follow a plant-based diet for 16 weeks. Researchers will track c…

This study looks at whether eating almonds every day for 12 weeks can help people with metabolic syndrome by improving gut health and lowering inflammation. About 80 adults aged 35-60 with signs of metabolic syndrome will participate. Researchers will measure changes in gut barri…

This study looks at whether taking blueberry powder can help overweight or obese people with signs of metabolic syndrome. The researchers want to see if blueberries change gut bacteria in a way that improves blood sugar, insulin, and cholesterol levels. About 59 adults will take …

This study looks at whether a protein supplement called carnitine can help reduce hardening of the arteries in teenagers at high risk for future heart disease. About 90 teens aged 11-21 with high triglycerides will take carnitine or a placebo. The goal is to see if carnitine can …

This study tests a program called FIT Families, designed to help African American teens (ages 12-17) with obesity and their caregivers lose weight and improve health. The program is culturally tailored and delivered by community health workers. About 360 teens and their caregiver…

This study compares two weight-loss surgeries for people with severe obesity (BMI over 45). It looks at how much weight is lost, how health problems like diabetes and high blood pressure improve, and the risk of side effects like malnutrition. The goal is to find which surgery is…

This study tests a video-based healthy lifestyle program for adults aged 50 to 74 who are overweight and have conditions like prediabetes, diabetes, or high blood pressure. Participants use a tablet and fitness tracker at home, and some get extra support from a coach by video or …

This study tests whether portable devices like handheld ultrasound and blood glucose monitors can help doctors find chronic diseases earlier than standard care. Two hundred adults aged 18 to 75 with conditions like prediabetes or high blood pressure will use the devices or receiv…

This study tests whether coaching mothers on feeding and sleep habits can prevent obesity in Latino infants. About 256 mothers and their newborns will receive group or text-based support during the first two years. The goal is to help babies reach healthy weights and reduce futur…

This study is testing a digital health system called STELA that helps adults without heart disease lower their risk factors like obesity, high cholesterol, and insulin resistance. About 100 participants will get a full health check, a personalized prevention plan, and support thr…

This study looks at whether taking a daily extract of yerba mate can improve health markers like weight, blood sugar, and cholesterol in overweight adults. 80 people aged 40-65 will take either the extract or a placebo for 90 days. Researchers will measure changes in body fat, bl…

This study looks at whether a simple, home-based walking program can help improve blood sugar, cholesterol, and body measurements in people living with HIV who also have metabolic syndrome. Researchers will enroll 50 adults (with and without HIV) and ask them to gradually increas…

This study looks at why storing fat in and around organs like the liver affects some people's health more than others. Researchers will measure insulin sensitivity and inflammation in 144 lean and obese adults. The goal is to better understand these differences to help develop fu…

This study is a review of many smaller studies that looked at what happens when people replace animal proteins (like meat, dairy, and eggs) with plant proteins (like beans, nuts, and seeds). The goal is to see if this simple swap can improve blood sugar, cholesterol, blood pressu…

This study looks at whether teens and young adults with Polycystic Ovary Syndrome (PCOS) have more fat in their liver than those without PCOS. Researchers will use MRI scans and other tests to measure liver fat, insulin resistance, and cholesterol problems. The goal is to better …

This study looks at how pretzels made with safflower oil and soy affect energy use in postmenopausal women who are overweight and have metabolic syndrome. Twenty women will eat different pretzels for one month each to see how their bodies digest them. The goal is to learn if thes…

This study screened over 16,600 adults in Spain (ages 45-70) with at least one risk factor (like high blood pressure or smoking) but no known heart disease. Half received advanced ultrasound and urine tests to find hidden artery and kidney problems. The goal is to see if early de…

This study looks at whether eating frozen raspberries every day can positively change gut bacteria and improve markers of metabolic syndrome (like blood sugar and cholesterol) in overweight or obese adults. About 59 healthy but overweight men and women will either eat raspberries…

This study looks at what happens when people who regularly drink sugary sodas switch to drinks sweetened with stevia or aspartame. Researchers want to see if these sugar substitutes change metabolism or gut bacteria for better or worse. About 41 healthy adults who drink 4 cans of…

This study looks at how different parts of dairy fat affect inflammation in adults with metabolic syndrome or obesity. Participants eat a high-fat meal and have their blood tested over six hours to measure inflammatory markers. The goal is to understand which dairy components mig…

This study looks at how eating pulses (like beans and lentils) changes the bacteria in your gut and affects your appetite. Researchers will measure gut microbes, appetite hormones, and other health markers in 44 overweight adults. The goal is to understand how pulses might help w…

This study re-examines 317 adults with type 2 diabetes who were first checked for fatty liver disease a few years ago. Researchers will use advanced scans and blood tests to see if their liver condition has improved, worsened, or stayed the same. The goal is to find patterns and …

This study looks at how eating cheese compared to a non-dairy cheese substitute changes inflammation levels over six hours. Researchers will measure inflammatory markers in the blood of 20 adults with metabolic syndrome or obesity. The goal is to understand the short-term effects…

This study follows 500 adults with obesity who are trying to lose weight. Researchers collect information like body measurements, blood tests, and lifestyle habits to find out what helps people succeed. The goal is to create personalized weight loss plans based on each person's u…