METABOLIC SYNDROME

This study is testing a healthy lifestyle program delivered through a patient's online medical record. It aims to see if a video-based program alone, or with remote coaching, helps adults aged 50-74 lose weight and improve their health to lower the risk of chronic diseases like d…

This study is testing whether a dietary supplement containing inositols and alpha-lactalbumin can help improve health markers in people with metabolic syndrome who are at risk for heart scarring. It will look at effects on body weight, blood sugar, and blood pressure. The study i…

This study is testing whether a 6-month home-based walking program can improve metabolic health markers like blood sugar and cholesterol in people with and without HIV. Participants will gradually increase their daily steps to about 10,000, tracked with an activity monitor. The g…

This study is testing a family-based program called FIT Families, designed specifically for African American teens with obesity and their caregivers. It compares this program to a standard support group to see which is better at helping families lose weight, become more active, a…

This study is testing whether a protein supplement called carnitine can reduce artery stiffness in teenagers who are at risk for future heart problems. Researchers will give carnitine or a placebo to 90 teens with high triglycerides for six months to see if it improves artery hea…

This study is testing whether a concentrated extract from yerba mate, a traditional tea, can improve health markers in overweight adults. 80 participants will take either the extract or a placebo pill daily for 90 days. Researchers will measure changes in weight, body fat, blood …

This study is testing a lifestyle coaching program designed to help people with both metabolic syndrome and chronic kidney disease. The program focuses on improving diet and physical activity. Researchers want to see if this coaching can reduce waist size and help preserve kidney…

This study aims to see if combining time-restricted eating (limiting daily food intake to a specific window) with high-intensity interval training (short bursts of intense exercise) can improve health in people with metabolic syndrome. Researchers will compare these approaches in…

This study is testing whether a one-year course of a dietary supplement called spermidine can help older adults with heart disease. Spermidine is a natural compound found in foods like whole grains and nuts. Researchers will check if it improves heart function, muscle mass, physi…

This study compares two different types of stomach surgery for people with severe obesity. Researchers want to see which procedure leads to better weight loss and improvement in health problems like diabetes and high blood pressure, while also checking which one causes fewer nutr…

This study is testing whether switching to a plant-based diet can improve heart health and reduce inflammation in people who have received a kidney transplant. Researchers are helping 25 participants follow the diet for at least 16 weeks, with training and support. They will meas…

This study is testing whether portable ultrasound and blood glucose monitoring devices can help doctors detect chronic conditions like diabetes and heart disease earlier than standard care. 200 participants at risk for these conditions will use the devices at home for 6 months wh…

This study aims to understand if adolescents and young adults with Polycystic Ovary Syndrome (PCOS) are more likely to have high liver fat and related metabolic problems like insulin resistance. Researchers will compare 40 young people with PCOS to 40 without it, using scans and …

This study aims to understand what factors help people with obesity succeed at losing weight. Researchers will follow 500 adults from a weight loss clinic, collecting detailed health and lifestyle information. The goal is to use this data to build better, more personalized weight…

This study aims to understand why storing fat around organs like the liver affects some people's health more than others, potentially leading to conditions like diabetes and heart disease. Researchers are comparing lean and obese individuals, some with and some without metabolic …

This study is checking back with 317 people who have type 2 diabetes to see how their liver health has changed over several years. Researchers are not testing a treatment; instead, they are using scans and blood tests to understand why some people develop serious liver disease an…

This study is investigating whether eating blueberry powder can improve the mix of bacteria in your gut and, in turn, help with conditions related to being overweight, like high blood sugar and cholesterol. Researchers are comparing blueberry powder to a placebo powder in 59 over…

This study aims to understand how eating cheese compared to a non-dairy cheese substitute affects inflammation in the hours after a meal. It involves 20 adults who have risk factors for metabolic syndrome or obesity. Participants eat one type of cheese on separate test days, and …

This study aims to understand if swapping sugary drinks for ones sweetened with stevia or aspartame affects metabolic health and gut bacteria. It involves 41 healthy adults who regularly drink soft drinks. Participants replace their usual sugary drinks with assigned beverages for…

This study aims to understand if eating frozen raspberries daily can improve the gut bacteria and metabolic health of overweight or obese adults. Researchers will compare a group eating raspberries to a group following their usual diet, measuring changes in blood sugar, cholester…

This study aims to understand how specific components in dairy fat might influence inflammation in the body after eating a high-fat meal. It involves 38 adults with obesity or metabolic syndrome who will drink different test shakes on separate days. Researchers will measure marke…

This small pilot study aims to see if it's practical to test different mind-body exercise programs for people with metabolic syndrome. Researchers are testing four approaches: a walking program, a mindfulness program, a combined program, or no program. The main goal is to learn i…

This study aims to understand how eating beans (like lentils and chickpeas) affects the bacteria in your gut and how full you feel after meals. Researchers are comparing a diet with beans to one without beans in 44 overweight adults. They will measure changes in gut bacteria, app…

This project is not a new treatment trial, but a large-scale analysis of past research. Researchers are compiling and reviewing results from many existing diet studies to understand if replacing animal protein (like meat and dairy) with plant protein (like beans and nuts) leads t…